| Zhou Jieping,Gao Ning,Qi Zhongyu,et al.Application of the ArcherQA 3D dosimetric verification system in dosimetric verification of VMAT plans[J].Chinese Journal of Radiological Medicine and Protection,2025,45(6):551-557 |
| Application of the ArcherQA 3D dosimetric verification system in dosimetric verification of VMAT plans |
| Received:September 24, 2024 |
| DOI：10.3760/cma.j.cn112271-20240924-00379 |
| KeyWords:Monte Carlo algorithm Dosimetric verification Volumetric Modulated Arc Therapy |
| FundProject:国家自然科学基金项目(12275372);安徽省重点研究与开发计划(2023s07020020);中国科学技术大学双一流医学物理与生物医学工程交叉学科平台(YD2140000601);2020年中国科学技术大学新医学创新团队项目(YD2140002002) |
| Author Name | Affiliation | E-mail | | Zhou Jieping | Department of Radiation Oncology, the First Affiliated Hospital of USTC (Anhui Provincial Hospital), Hefei 230031, China
Department of Radiation Oncology, Anhui Provincial Cancer Hospital, Hefei 230031, China | | | Gao Ning | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026, China | | | Qi Zhongyu | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026, China | | | Ren Qiang | Anhui Wisdom Technology Co., Ltd, Hefei 230026, China | | | Pei Xi | Anhui Wisdom Technology Co., Ltd, Hefei 230026, China | | | Xu Xie | School of Nuclear Science and Technology, University of Science and Technology of China, Hefei 230026, China | | | Wu Aidong | Department of Radiation Oncology, the First Affiliated Hospital of USTC (Anhui Provincial Hospital), Hefei 230031, China
Department of Radiation Oncology, Anhui Provincial Cancer Hospital, Hefei 230031, China | flkaidongwu@163.com |
|
| Hits: 140 |
| Download times: 46 |
| Abstract:: |
| Objective To rapidly and accurately detect volumetric modulated arc therapy (VMAT) plans with potentially inaccurate radiation doses. Methods The measurement-based dosimetric verification result of 196 VMAT plans obtained using ArcCHECK phantoms were retrospectively collected. Independent dosimetric calculation and verification were conducted for these plans using the ArcherQA system based on a fast Monte Carlo algorithm. The gamma passing rates of dosimetric verification using ArcCHECK phantom and the ArcherQA system were compared, followed by their correlation analysis and linear regression fitting. The ArcherQA system's gamma passing rate threshold used to detect positive dosimetric verification result obtained using ArcCHECK phantoms, as well as the specificity of the detection, were calculated. Based on this gamma passing rate threshold, another 50 VMAT plans were selected as a test set to assess the ArcherQA system's ability to detect positive measurement-based dosimetric verification result. Results The average gamma passing rates for the dosimetric verification of the VMAT plans using the ArcherQA system and ArcCHECK phantoms were 97.28% and 96.57% (3%/3 mm, TH=10%), respectively. Both rates had a correlation coefficient of 0.71 (P < 0.01) and a linear fitting coefficient of 0.54 (R2=0.51). When the gamma passing rate for dosimetric verification using ArcCHECK phantoms was set at 90% (3%/2 mm, TH=10%), the gamma passing rate threshold for dosimetric verification using the ArcherQA system should be adjusted to 94.8% to detect all VMAT plans with positive dosimetric verification result obtained using ArcCHECK phantoms, with a specificity of 67.8%. Using this threshold, the ArcherQA system detected all VMAT plans in the test set for which ArcCHECK phantom-based measurement yielded positive dosimetric verification result. Conclusions By determining an appropriate gamma passing rate threshold, the ArcherQA system can rapidly and accurately detect VMAT plans with potentially inaccurate doses, thus ensuring treatment accuracy and improving work efficiency. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
