| Luo Hui,Ma Yichen,Ma Leijie,et al.Research advances in FLASH radiotherapy-related clinical trials[J].Chinese Journal of Radiological Medicine and Protection,2024,44(10):891-895 |
| Research advances in FLASH radiotherapy-related clinical trials |
| Received:March 04, 2024 |
| DOI：10.3760/cma.j.cn112271-20240304-00085 |
| KeyWords:FLASH radiotherapy Clinical trial Safety Radiation damage Research advance |
| FundProject: |
| Author Name | Affiliation | E-mail | | Luo Hui | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Ma Yichen | Department of Clinical Medicine, Xinjiang Medical University, Urumqi 830000, China | | | Ma Leijie | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Mao Ronghu | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Lei Hongchang | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Liu Han | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Zhang Yanping | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Xu Meng | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | | | Ge Hong | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | zlyygehong0199@zzu.edu.cn | | Yang Chengliang | Department of Radiation Oncology, Affiliated Cancer Hospital of Zhengzhou University, Zhengzhou 450008, China | |
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| Abstract:: |
| FLASH radiotherapy (FLASH-RT) has garnered considerable attention globally in recent years. Compared to conventional radiotherapy, FLASH-RT can deliver the total radiation dose to the target volume in an extremely short time, reducing the radiation-induced damage to normal tissue while maintaining similar anti-tumor effects. FLASH-RT has been in the clinical trial stage, with several clinical research result being reported. Based on the collected global clinical research result of FLASH-RT in recent years, this study systematically reviewed FLASH-RT's safety, radiation-related side effects, treatment efficacy, opportunities, and challenges in clinical trials. |
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