Zhang Yurong,Yuan Qianqian,Gao Jianbo,Liu Jie.Application value of deep learning reconstruction algorithm in CT imaging of abdominal phantoms[J].Chinese Journal of Radiological Medicine and Protection,2023,43(8):645-652
Application value of deep learning reconstruction algorithm in CT imaging of abdominal phantoms
Received:December 26, 2022  
DOI:10.3760/cma.j.cn112271-20221226-00498
KeyWords:Radiation dosage  Tomography, X-Ray Computer  Abdomen  Phantom
FundProject:河南省卫生健康委员会科技攻关项目(212102310142)
Author NameAffiliationE-mail
Zhang Yurong Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhenzhou 450052, China  
Yuan Qianqian Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhenzhou 450052, China  
Gao Jianbo Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhenzhou 450052, China  
Liu Jie Department of Radiology, First Affiliated Hospital of Zhengzhou University, Zhenzhou 450052, China liujieict@163.com 
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Abstract::
      Objective To explore the value of the deep learning image reconstruction (DLIR) algorithm in improving the CT image quality of abdominal phantoms under different radiation doses by comparing the DLIR algorithm with the conventional Adaptive Statistical Iterative Reconstruction-V (ASIR-V) technique.Methods Two groups with tube voltages of 100 kV and 120 kV (also referred to as the 100 kV and 120 kV groups, respectively) were involved. Each group was further divided into six subgroups based on different volumetric CT dose indices (CTDIvol:2, 4, 6, 8, 10 and 15 mGy). Subsequently, CT images based on the filtered back projection (FBP) algorithm were obtained and were then reconstructed using the ASIR-V algorithm with different weights (ASIR-V 50%, 80%, and 100%) and the DLIR algorithm with different levels (DLIR-L, M, and -H). As a result, 84 groups of images were obtained in total. Afterward, this study compared and analyzed the variations in CT values, noise, signal-to-noise ratios (SNRs), contrast-to-noise ratios (CNRs), and subjective scores of various parts in various CTDIvol subgroups under different reconstruction conditions. In addition, the subjective scores of the image quality were compared using the Kruskal-Wallis H test, while objective indices and radiation doses were compared through the univariate analysis of variance (ANOVA) and the paired t test.Results Under the same tube voltage, there were statistically significant differences in the noise, SNRs, and CNRs of various parts in various CTDIvol subgroups under different reconstruction conditions (F=415.39, 315.30, P < 0.001), while there was no statistically significant difference in the noise, SNRs, and CNRs of images constructed using ASIR-V 50% and DLIR-L (P > 0.05). Under different tube voltages, the subjective scores of both groups show statistically significant differences (100 kV group: H=13.47, P =0.036; 120 kV group:H=12.99, P=0.043). Moreover, two physicians offered consistent subjective scores, with Kappa values > 0.70. Among these images, DLIR-H images showed the highest subjective scores, followed by DLIR-M and ASIR-V 50% images, which had roughly consistent subjective scores. Moreover, the subjective scores of the 100 kV group were slightly higher than those of the 120 kV group. With the ASIR-V 50% images of the subgroup with a CTDIvol of 15 mGy as references, the DLIR-L, -M, and -H reduced radiation doses by more than 30%, 70% and 85%, respectively on the premise that diagnostic requirements were met.Conclusions The DLIR algorithm can not only significantly reduce the image noise and improve the image quality, but also effectively decrease the radiation doses on the premise of meeting the diagnostic requirements. It is recommended that 100 kV tube voltage combined with a medium- or high-level DLIR algorithm should be applied to low-dose abdominal CT scans in clinical applications.
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