Tan Tingting,Yang Nan,Wang Chunxiang.Preliminary study on calculating size-specific dose estimate values based on age in children's head[J].Chinese Journal of Radiological Medicine and Protection,2022,42(11):897-902
Preliminary study on calculating size-specific dose estimate values based on age in children's head
Received:June 19, 2022  
DOI:10.3760/cma.j.cn112271-20220619-00255
KeyWords:Children  Head  Computed tomography  Age  Size-specific dose estimate
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Author NameAffiliationE-mail
Tan Tingting Department of Radiology, Tianjin Children's Hospital, Tianjin 300134, China  
Yang Nan Department of Radiology, Tianjin Children's Hospital, Tianjin 300134, China 18202549033@163.com 
Wang Chunxiang Department of Radiology, Tianjin Children's Hospital, Tianjin 300134, China  
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Abstract::
      Objective To investigate the feasibility of size-specific dose estimate of head based on pediatric patients' age.Methods A retrospective study was conducted on plain head CT scans of 210 patients in Tianjin Children' s Hospital from January to March in 2022. The volume CT dose index (CTDIvol) values, age and sex of the patients were recorded. The anteroposterior diameter (AP) and lateral diameter(LAT), aera and CT value in the middle slice of the scan region were measured on the workspace. According to the AAPM reports 220 and 293, the water equivalent diameter (DW) of head,size-specific conversion factors (fH16measured), and size-specific dose estimate (SSDEmeasured) were calculated. The effective diameter (Deff;WHO) was calculated for male and female individuals using the ralationship between the standard head circumference and age of children provided by World Health Organization (WHO). The effective diameter (Deff;WHO) was converted into a water equivalent diameter (DW;WHO), using a correlation established from the Deff and DWwhich were measured in 210 image sets of male and female patients. Then the corresponding fH16WHO and SSDEWHO of head can be calculated. The correlation between DW and DW;WHO, fH16measured and fH16WHO, the correlation and consistency between SSDEmeasured and SSDEWHO, and the conversion relationship between age and fH16WHO were analyzed for male and female patients.Results A significant correlation were found between the measured DW and DW;WHO(female: r=0.917, P<0.01; male: r=0.873, P<0.01), fH16measured and fH16WHO(female: r=0.916, P<0.01; male: r=0.883, P<0.01), SSDEmeasured and SSDEWHO(r=0.991, P<0.01; male: r=0.992, P<0.01). The Bland-Altman test indicated that there was good coherence between SSDEmeasured and SSDEWHO. Maximal mean root-mean-square errors of SSDEmeasured and SSDEWHO were 5.61% in female and 5.25% in male. The conversion relationship between fH16WHO and patient age in different genders was obtained by curve fitting.Conclusion The SSDE of head in pediatric patients can be estimated simply and accurately by directly using the patient's age.
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