Zheng Fang,Zhong Heli,Chen Hongtao,Li Longxing,Zhang Ding,Fu Xin,Shi Yabin,Li Zihuang.Impact of the Varian real-time position management respiratory gating system on radiotherapy planning dosimetry[J].Chinese Journal of Radiological Medicine and Protection,2022,42(9):685-690
Impact of the Varian real-time position management respiratory gating system on radiotherapy planning dosimetry
Received:May 16, 2022  
DOI:10.3760/cma.j.cn112271-20220516-00207
KeyWords:Real-time position management respiratory gating  Portal Dosimetry  Chest and abdominal tumors  Radiotherapy plan verification
FundProject:深圳市科技研发资金(JCYJ20180305180540801)
Author NameAffiliationE-mail
Zheng Fang Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Zhong Heli Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Chen Hongtao Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Li Longxing Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Zhang Ding Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Fu Xin Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Shi Yabin Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China  
Li Zihuang Department of Radiation Oncology, Shenzhen People's Hospital, The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology, Shenzhen 518020, China li.zihuang@szhospital.com 
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Abstract::
      Objective To study the impact of the Varian real-time position management (RPM) respiratory gating system on radiotherapy planning dosimetry.Methods The radiotherapy plans of 40 cases with thoracic or abdominal tumors were retrospectively selected in this study.The motion phantom for quality control was adopted to generate respiratory gating signals,and the 30%-60% stable phase at the end of expiratory was selected as the respiratory gating window.The dose verification for the abovementioned radiotherapy plans was performed using the Portal Dosimetry (PD) system under RPM respiratory gating mode with the Edge accelerator.Afterwards,dose analysis was performed with different γ passing rate criteria and the distribution characteristics of γ values were analyzed.Finally,the verification results between the non-gating mode and the gating mode were compared.Results Under the respiratory gating mode,the passing rates of all intensity-modulated radiation therapy/volumetric-modulated arc therapy (IMRT/VMAT) plans with or without flattening filters were over 95.5% by γ criteria of (3%,3 mm) or (3%,2 mm) and were over 90% by stricter γ criteria of (2%,2 mm).All plans met the clinical requirements recommended by the American Association of Physicists in Medicine (AAPM).The passing rates of dose verification under non-gating mode were slightly better than those under respiratory gating mode,and the differences between the two modes were statistically significant (3%/3 mm,Z=-1.45;3%/2 mm,Z=-2.86;2%/2 mm,Z=-3.70;1%/1 mm,Z=-4.52;P<0.05).There was no significant difference in the minimum and maximum values of γ and the share of γ > 1.5 of plan verification result under the two modes.However,the average value and standard deviation of the γ were generally smaller under the non-gating mode.Conclusions The impact of the introduction of RPM respiratory gating technology on dose is clinically acceptable,and the execution of these plans in this gating mode is safe and reliable.
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