Wu Fan,Tang Bin,Yang Feng,Wu Junxiang.Analysis of dosimetric verification results of three verification systems for stereotactic body radiation therapy[J].Chinese Journal of Radiological Medicine and Protection,2022,42(9):678-684
Analysis of dosimetric verification results of three verification systems for stereotactic body radiation therapy
Received:June 24, 2022  
DOI:10.3760/cma.j.cn112271-20220624-00267
KeyWords:Stereotactic body radiation therapy  Dosimetric verification  Target volume  Calculation grid size  Dose threshold
FundProject:四川省重点研发项目(2021YFG0168,2021YFG0320,2022YFS0047);肿瘤医工创新基金(ZYGX2021YGCX002)
Author NameAffiliationE-mail
Wu Fan Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Tang Bin Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Yang Feng Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Wu Junxiang Radiation Oncology Key Laboratory of Sichuan Province, Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China wujx610@qq.com 
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Abstract::
      Objective To compare the effects of parameters,such as planning target volume (PTV),calculation grid size,and dose threshold,on the dosimetric verification result of three dosimetric verification systems ArcCHECK,SRS MapCHECK,and 3DMap for stereotactic body radiation therapy (SBRT).Methods Based on the dosimetric verification result of the SBRT plans of 50 patients,this study compared the effects of PTV (<25 cm3 and ≥ 25 cm3),calculation grid size (1.0,1.5,and 2.0 mm),and dose threshold (5%,10%,and 15%) on the γ passing rates of the three dosimetric verification systems at five criteria,i.e.,3 mm/3%,3 mm/2%,3 mm/1%,2 mm/3%,and 2 mm/2%.Results The changes in PTV affected 3DMap more significantly.With an increase in PTV,the γ passing rates of 3DMap at the criteria of 3 mm/3%,3 mm/2%,2 mm/3%,and 2 mm/2% increased by 2.2%,2.2%,4.4%,and 4.7%(t=-2.76,-2.17,-4.72,-3.86,P<0.05),respectively.The increase in the calculation grid from 1.0 mm to 1.5 mm had greater effect on MapCHECK,with the γ passing rates at the criteria of 3 mm/3%,3 mm/2%,3 mm/1%,2 mm/3% and 2 mm/2% decreased by 0.7%,1.1%,1.7%,0.9%,1.5%(t=-6.15,-6.23,-5.98,-5.11,-8.34,P<0.05),respectively.The increases in the calculation grid from 1.0 mm to 2.0 mm had greater impact on ArcCHECK,with the γ passing rates at the criteria of 3 mm/3%,3 mm/2%,3 mm/1%,2 mm/3%,2 mm/2% decreased by 1.0%,1.7%,2.4%,1.7%,2.7%(t=-4.75,-7.3,-8.63,-7.11,-8.26,P<0.05),respectively.The increase in the dose threshold from 5% to 10% had greater impact on ArcCHECK,with the γ passing rates at the criteria of 3 mm/3%,3 mm/2%,2 mm/3% and 2 mm/2% decreased by 1.1%,1.4%,2.5%,and 3.0%(t=5.20,5.68,8.17,9.99,P<0.05),respectively.Moreover,the increase in the dose threshold from 5% to 15% had more impact on 3DMap,with the γ passing rates at the criteria of 3 mm/3%,3 mm/2%,2 mm/3%,and 2 mm/2% decreased by 1.6%,1.7%,2.8%,and 3.2%(t=3.25,2.98,4.40,4.21,P<0.05),respectively.Conclusions Target volume,calculation grid,and dose threshold are influencing factors in the dosimetric verification of three dosimetric verification systems for SBRT.Therefore,the effects of these parameters should be considered for different verification systems in clinical applications.
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