| Chen Xiaoyu,Cao Guoquan,Deng Qingshan,Zhang Mingyue,Yang Yunjun,Wang Zhenzhang.Application of 10 s contrast agent injection protocol combined with 80 kV tube potential in carotid artery CTA procedure[J].Chinese Journal of Radiological Medicine and Protection,2021,41(4):299-303 |
| Application of 10 s contrast agent injection protocol combined with 80 kV tube potential in carotid artery CTA procedure |
| Received:July 17, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.04.011 |
| KeyWords:Carotid artery CT angiography Contrast medium Radiation dose Tube voltage |
| FundProject:浙江省卫生创新人才项目（20161107） |
| Author Name | Affiliation | E-mail | | Chen Xiaoyu | Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China | | | Cao Guoquan | Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China | | | Deng Qingshan | Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China | | | Zhang Mingyue | Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China | | | Yang Yunjun | Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China | | | Wang Zhenzhang | Department of Radiology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, China | 357379282@qq.com |
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| Abstract:: |
| Objective To investigate the feasibility of tube potential of 80 kV combined with personalized contrast agent protocol in carotid artery CT angiography (CTA). Methods A total of 136 consecutive patients undergoing neck CTA were prospectively enrolled in this study. The patients were randomly divided into Groups A, B, C and D. Tube potential of 100 kV and 15 s contrast agent injection protocol was used for Group A (53 cases) as conventional group, while tube voltage of 80 kV and 10 s contrast agent injection protocol was used for Groups B, C and D as experimental groups, with the contrast agent dosages of 20, 25 and 30 ml used according to the body weights of ≤ 50 kg(Group B, 20 cases), 50-70 kg (Group C, 38 cases), and 70-90 kg (Group D, 25 cases), respectively. The subjective and objective evaluation results of image quality and the effective doses were compared among the four groups. Results The effective doses in Groups B, C and D were 1.54±0.91, 1.89±1.08 and 2.14±1.27 mSv, respectively, significantly lower than that in Group A[(5.66±0.56) mSv] (F=169.34, P<0.05). The image quality of four groups met the requirements of clinical diagnosis. No significant differences were found in subjective evaluation and diagnostic efficacy of the four groups (P>0.05). The CT number of carotid artery, signal-to-noise ratio and contrast-to-noise ratio of the neck region were significantly lower in Groups B, C and D compared with Group A (F=14.9, 12.94, 14.43, P<0.05). The CT numbers of target carotid vessel were all higher than 250 HU. Conclusions The scanning protocol of low tube potential (80 kV) combined with 10 s contrast agent injection protocol could not only reduce the doses of radiation and contrast agent, but also preserve the diagnosis effect. Thus, this scanning protocol was feasible and valuable in clinical application. |
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