| Liu Yun,He Chuang,Liang Qinghua,et al.Differences in dosimetric parameters between 125I seed implantation with degradable catheters and free-hand[J].Chinese Journal of Radiological Medicine and Protection,2021,41(1):62-65 |
| Differences in dosimetric parameters between 125I seed implantation with degradable catheters and free-hand |
| Received:February 24, 2020 Revised:October 15, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2021.01.013 |
| KeyWords:125I seeds Degradable catheter Brachytherapy CT-guided |
| FundProject:重庆市技术创新与应用发展（科技扶贫专项）（CSTC2019JSCX-KJFP0005） |
| Author Name | Affiliation | E-mail | | Liu Yun | Department of Oncology, Daping Hospital, Army Medical University, Chongqing 400042, China | | | He Chuang | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | longtoo123@qq.com | | Liang Qinghua | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | | | Chen Yuxiao | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | | | Li Liangshan | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | | | Yuan jing | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | | | Li Tingyuan | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | | | Huang Xuequan | Center of Minimally Invasive, Southwest Hospital, Army Medical University, Chongqing 400038, China | |
|
| Hits: 3924 |
| Download times: 1637 |
| Abstract:: |
| Objective To compare the differences in dosimetric parameters of target areas between 125I seed implantation with degradable catheters and by hand under the assistance of a real-time intraoperative treatment planning system (TPS). Methods Forty-two simulated lesions were divided into a degradable catheter group and a free-hand group, with twenty-one lesions in each group.125I seeds were implanted according to the TPS.The pre-plan and post-implant dosimetric parameters were collected, including the minimum dose (Dmin), maximum dose (Dmax), mean dose (Dmean), conformal index (CI), external index (EI), homogeneity index (HI), minimum prescription dose delivered to 90% of the target volume (D90), and the mean percentage of volume receiving 90% of the prescription doses (V90). The Bland-Altman method was employed to analyze the consistency of pre-plan and post-implant dosimetric parameters and the Wilcoxon rank-sum test was used for the comparison of the two groups.Results According to the Bland-Altman analysis, the dosimetric parameters of the two groups were all in agreement before and after seed implantation except for the Dmin and V90 of the free-hand group.Furthermore, the degradable catheter group had smaller error ranges of Dmax (Z=-3.824, P<0.005), CI (Z=-1.962, P<0.005), HI (Z=-2.352, P<0.005), D90 (Z=-2.453, P<0.005), and V90 (Z=-3.159, P<0.005). Conclusions The dosimetric parameters of 125I seed implantation with degradable catheters under the assistance of real-time TPS have good pre-plan and post-implant consistency and smaller error ranges. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
