Zhang Yu,Liu Changsheng,Guo Kelei,et al.Application value of post-discharge chest low-dose CT for patients with COVID-19[J].Chinese Journal of Radiological Medicine and Protection,2020,40(10):789-793
Application value of post-discharge chest low-dose CT for patients with COVID-19
Received:March 30, 2020  
DOI:10.3760/cma.j.issn.0254-5098.2020.10.010
KeyWords:COVID-19  Low dose  Chest  Follow-up  Computed tomography
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Author NameAffiliationE-mail
Zhang Yu Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China  
Liu Changsheng Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China  
Guo Kelei Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China  
Peng Zhoufeng Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China  
Zha Yunfei Department of Radiology, Renmin Hospital of Wuhan University, Wuhan 430060, China zhayunfei999@126.com 
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Abstract::
      Objective To explore the value of chest low-dose CT (LDCT) in post-discharge follow-up assessments of patients with coronavirus disease 2019 (COVID-19 ). Methods The chest CT findings of 58 patients with COVID-19 from March 17 to March 25, 2020 at Remin Hospital of Wuhan University were retrospectively analyzed. Two radiologists independently scored the subjective image quality on a 5-point Likert scale. The signal-to-noise ratio (SNR) and SDair of images and the CT radiation dose parameters were calculated, including the CT volume dose index (CTDIvol), dose length product (DLP), and effective radiation dose (E ). Results The subjective image quality scores on CT images obtained before and after discharge by readers 1 and 2, were 4.45±0.22, 3.88±0.33 (P>0.05) and 4.37±0.18, 3.91±0.35 (P>0.05 ), respectively. The SNR and SDair in LDCT after discharge were 4.39±0.95 and 7.19±2.41, which were significantly lower than those in routine chest CT before discharge (5.14±1.06, Z=-5.551, P<0.001; 6.48±1.57, Z=-3.217, P<0.001 ). All of the obtained images were sufficient for diagnosis. The CTDIvol, DLP, and E in LDCT were significantly lower than those in routine CT [(2.41±0.09), (10.53±1.03)mGy, Z=-6.568, P<0.001; (88.03±5.33), (338.74±34.64)mGy·cm, Z=-6.624, P<0.001; and (1.23±0.17), (4.74±0.48)mSv, Z=-5.976, P<0.001 ]. Conclusions Patients with COVID-19 can be followed up with low-dose chest CT after discharge.
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