| Luo Kun,Lei Ziqiao,Dong Qian,Ning Xianying,Yang Ming,Kong Xiangchuang,Wu Hongying,Yu Jianming,Zheng Chuansheng.Application of chest low-dose CT screening of Corona Virus Disease 2019 with a third-generation dual-source scanner[J].Chinese Journal of Radiological Medicine and Protection,2020,40(10):783-788 |
| Application of chest low-dose CT screening of Corona Virus Disease 2019 with a third-generation dual-source scanner |
| Received:March 26, 2020 |
| DOI：10.3760/cma.j.issn.0254-5098.2020.10.009 |
| KeyWords:Corona Virus Disease 2019(COVID-19) Dual-source CT Low dose Radiation dose |
| FundProject: |
| Author Name | Affiliation | E-mail | | Luo Kun | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Lei Ziqiao | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | leiziqiaowhxh@163.com | | Dong Qian | Imaging Center, Wuhan Children's Hospital(Wuhan Maternal and Child Healthcare Hospital), Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430016, China | | | Ning Xianying | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Yang Ming | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Kong Xiangchuang | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Wu Hongying | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Yu Jianming | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | | | Zheng Chuansheng | Department of Radiology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei Province Key Laboratory of Molecular Imaging, Wuhan 430022, China | |
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| Abstract:: |
| Objective To investigate the application value of third-generation dual-source CT(3-G DSCT) low-dose scan mode combined with iterative reconstruction technology in the screening of COVID-19 and to evaluate the radiation dose.Methods One hundred and twenty patients suspected of COVID-19 from December 2019 to February 2020 were retrospectively analysed and randomly divided into two groups (test group and conventional group, 60 patients in each ). The parameters for test group included 3-G DSCT, Turbo Flash scan mode, CARE kV, with reference 90 kV, pitch 2.0, and ADMIRE algorithm, while those parameters for conventional group included the 128-slice CT, conventional spiral scan mode, 120 kV, pitch 1.2, and FBP algorithm. The CT values of aorta, spinal posterior muscle, and subcutaneous fat, the aortic noise, signal-to-noise ratio (SNR), and contrast noise ratio (CNR) were compared to evaluate the image quality between two groups. Two experienced doctors scored the image quality using a double-blind method, and compared the CT dose index volume (CTDIvol), dose-length product (DLP), and effective dose (E) of the two groups. Results The CT value of the aorta and spinal posterior muscle and the aortic SNR in the test group were (45.38±4.77), (53.41±8.44) HU, and 2.82±0.59, and significantly higher than those in the conventional group [(39.68±6.26), (42.66±6.32) HU, 2.58±0.61, t=5.608,7.897,2.162, P<0.05 ]. The aortic noise, CNR and subjective scores between the two groups had no significant difference(P>0.05 ). The CTDIvol, DLP, and E in the test group were (3.09±1.02) mGy, (107.57±32.81) mGy·cm, (1.51±0.46) mSv, significantly lower than those in the conventional group [(7.00±1.80) mGy, (261.65±73.93) mGy·cm, (3.66±1.03) mSv; t=-14.680,-14.756,-14.756, P<0.05]. Conclusions In the screening of COVID-19, using low-dose scanning mode of 3-G DSCT combined with iterative reconstruction technology would provide diagnostic quality images and meanwhile effectively reduce the radiation dose and improve the SNR of the image. |
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