He Xiaolong,Xu Jian,Zhu Feng,Lyu Yingguo,Luo Kuangnan.Feasibility of pre-scan size-specific dose estimate in coronary computed tomography angiography[J].Chinese Journal of Radiological Medicine and Protection,2020,40(9):717-721
Feasibility of pre-scan size-specific dose estimate in coronary computed tomography angiography
Received:March 29, 2020  
DOI:10.3760/cma.j.issn.0254-5098.2020.09.012
KeyWords:Radiation dosage  Size-specific dose estimate  Angiography  Coronary artery disease
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Author NameAffiliationE-mail
He Xiaolong Department of Radiology, Quzhou People's Hospital, Quzhou 324000, China  
Xu Jian Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China hzxj_610@163.com 
Zhu Feng Department of Radiology, Quzhou People's Hospital, Quzhou 324000, China  
Lyu Yingguo Department of Radiology, Quzhou People's Hospital, Quzhou 324000, China  
Luo Kuangnan Shengshi Technology, Co., Ltd, Hangzhou 311100, China  
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Abstract::
      Objective To investigate the feasibility of optimization of coronary computed tomography angiography (CCTA) with pre-scan size-specific dose estimate(SSDE). Methods Ninety patients from Quzhou People's Hospital during March and May 2018 who underwent CCTA were defined as modelled patients,the regression equation of body mass index (BMI) and water-equivalent diameter (dw) were conducted and upper quartile of CTDIvol values was calculated. Other 67 patients were divided into two groups:control group (CCTA scan protocol, based on CTDIvol) and study group (CCTA scan protocol using SSDE). The image quality and radiation dose including breast dose (Dosebre) in two groups were assessed. Results The positive correlation was found between BMI and dw with a linear regression equation of dw=9.241 + 0.644×BMI(r=0.823,P<0.05), and the upper quartile of CTDIvol was 7.92 mGy. The proportions of high-level image quality were 94.10% (367/390) and 93.93% (402/428) in the control and study groups, respectively (P>0.05). The median signal to noise ratio (SNR) and contrast to noise ratio (CNR) were 21.08/24.39, 17.24/19.94 in the control and study groups, respectively (P>0.05). The CTDIvol, SSDE and Dbre of the study group were reduced by 37.04%, 35.77% and 37.37% compared with the control group, and statistically significant differences were found(z=-7.041, t=18.479, 15.079, P<0.05) among them. Conclusions The CCTA scan protocol based on the pre-scan SSDE can significantly reduce the radiation dose and provide the diagnostic image quality.
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