| Li Junyu,Wu Hao,Yang Jingxian,Li Tingting,Yu Songmao,Lu Zihong,Wang Meijiao,Li Chenguang,Li Weibo,Zhang Yibao.Evaluation of cost-effective ratio (imaging quality vs. radiation dose) of Varian cone beam CT based on figure of merit (FOM)[J].Chinese Journal of Radiological Medicine and Protection,2020,40(8):595-599 |
| Evaluation of cost-effective ratio (imaging quality vs. radiation dose) of Varian cone beam CT based on figure of merit (FOM) |
| Received:December 11, 2019 |
| DOI：10.3760/cma.j.issn.0254-5098.2020.08.004 |
| KeyWords:Image guided radiotherapy kV cone beam CT Radiation dose Image quality |
| FundProject:首都卫生发展科研专项（首发2018-4-1027）；教育部科技发展中心产学研创新基金-"智融兴教"基金（2018A01019）；国家自然科学基金（11505012，11905150，81672969）；国家重点研发计划资助项目（2019YFF01014405）；四川省科技计划资助项目（2018HH0099）；北京市自然科学基金（7172048，1202009） |
| Author Name | Affiliation | E-mail | | Li Junyu | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Wu Hao | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Yang Jingxian | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Li Tingting | The Fifth Medical Center of PLA General Hospital, Beijing 100039, China | | | Yu Songmao | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Lu Zihong | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Wang Meijiao | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Li Chenguang | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | | | Li Weibo | Institute of Radiation Medicine, Helmholtz Zentrum Mü
nchen-German Research Center for Environmental Health(GmbH), Neuherberg 185764, Germany | | | Zhang Yibao | Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China | ybzhang66@163.com |
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| Abstract:: |
| Objective To analyze and compare the radiation dose and image quality of kilo-voltage cone beam CT systems on different Varian accelerator platforms, providing data to support clinical decisions on selecting optimal protocols for image-guided radiotherapy based on cost-effective ratio (image quality/radiation dose). Methods The radiation dose and image quality of various CBCT systems and scanning protocols on Varian Edge, Truebeam and ix (new and old) LINACs were obtained using a CT dose index (CTDI) phantom combined with a CT ionization chamber and a Catphan604 phantom, respectively. Figure of merit (FOM) was used to evaluate the cost-effective ratio of the image guidance schemes. Results Considerable inter-system varieties of FOMs were observed, varying from 0.65 (Image Gently-full trajectory) to 48.46 (Image Gently-half trajectory). The inter-protocol varieties were also large, where the mean±SD was 22.14±13.47. Conclusions Considering the explicit inter-system and inter-protocol varieties, it is clinically favorable to evaluate the image guidance schemes based on machine-specific measurement. For instance, parameters and equipment with low CTDIw can be beneficial for dose-sensitive patients. High CNR regimen favors patients with high image quality requirements. For ordinary patients, cost-effective ratio in terms of FOM can be very helpful to guide the decision-making of clinical image-guided radiotherapy. |
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