Xu Jian,Wang Xiangquan,Yang Panfeng,Xie Yelei,Luo Kuangnan,Mao Dewang.Feasibility study for calculating size-specific dose estimates based on weight and body mass index in CT abdomen-pelvic examination of adult population[J].Chinese Journal of Radiological Medicine and Protection,2020,40(7):549-553
Feasibility study for calculating size-specific dose estimates based on weight and body mass index in CT abdomen-pelvic examination of adult population
Received:October 13, 2019  
DOI:10.3760/cma.j.issn.0254-5098.2020.07.011
KeyWords:Body mass index  Tomography,X-ray  Size-specific dose estimate
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Author NameAffiliationE-mail
Xu Jian Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China  
Wang Xiangquan Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China  
Yang Panfeng Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China  
Xie Yelei Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China  
Luo Kuangnan Hangzhou Shengshi Technology, Co., Ltd, 311199, China  
Mao Dewang Department of Radiology, Zhejiang Provincial People's Hospital, People's Hospital of Hangzhou Medical College, Hangzhou 310014, China hzxj_610@163.com 
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Abstract::
      Objective To explore the feasibility for taking weight and body mass index (BMI) to calculate the size-specific dose estimate (SSDE) in abdomen-pelvis CT examination. Methods 512 adult patients undergoing abdomen-pelvis CT examination were retrospectively analyzed. The in-house software based on MATLAB platform were used to calculate automatically water equivalent diameter (dw), size-dependent conversion factor (f), SSDE, together with their respective averaged values. The correlations between age, height, weight and BMI with dw were calculated by using Spearman correlation analysis. Two regression equations were established to calculate the SSDE (SSDEweight,SSDEBMI), one for the correlation of weight with dw based on first half of these cases and the other for that between BMI with dw based on another half as the cases to be verified. With reference of the SSDE derived from the in-house software, the averaged relative differences and root-mean-square errors in SSDEweightand SSDEBMI were calculated, respectively. Results No statistically significant correlation between age and dw (P>0.05) was shown, but weak correlation between height and dw(r=0.260,P<0.05), strong correlation between either weight or BMI with dw(r=0.879, 0.851,P<0.05). Two regression equations were described as dw=13.808+0.184×weight, dw=11.142+0.618×BMI. The mean SSDE, SSDEweight and SSDEBMI for the verified patients were (13.55±1.66) mGy, (13.84±2.03) mGy and (13.83±2.02) mGy, respectively. As compared to actual SSDE, the averaged relative differences in SSDEweight and SSDEBMI were 1.97% and 1.87%; 0.38% and 2.75% for male patients; 4.58% and 0.43% for female patients; 0.11% and 3.32% for patients with BMI<18.5 kg/m2; 1.92% and 2.06% for those with 18.5 kg/m2 ≤ BMI<24.0 kg/m2; 2.57% and 1.57% for those with 24 kg/m2 ≤ BMI<28.0 kg/m2; 3.28% and -1.36% for those with BMI ≥ 28.0 kg/m2. The averaged root-mean-square errors in SSDEweight and SSDEBMI were both 0.80 mGy; 0.65 and 0.67 mGy for male patients; 0.98 and 0.59 mGy for female patients; 0.73 and 1.03 mGy for underweight, 0.74 and 0.66 mGy for normal weight, 0.85 and 0.79 mGy for overweight, and 1.10 and 1.32 mGy for obesity. Conclusions Weight and BMI can be used as the surrogate dw to compute SSDE in adult abdomen-pelvis CT examination. However, Weight rather than BMI is more applied to male patients, and BMI is more suitable for female patients.
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