Li Junyu,Yu Songmao,Zhou Shun,Wu Hao,Gong Jian,Yang Jingxian,Yue Haizhen,Li Tingting,Du Yi.Application of optical surface monitoring system(OSMS) during postoperative radiotherapy for breast cancer patients immobilized with neck and thorax thermoplastic mask[J].Chinese Journal of Radiological Medicine and Protection,2020,40(7):524-528
Application of optical surface monitoring system(OSMS) during postoperative radiotherapy for breast cancer patients immobilized with neck and thorax thermoplastic mask
Received:December 11, 2019  
DOI:10.3760/cma.j.issn.0254-5098.2020.07.006
KeyWords:Breast neoplasms  Optical surface monitoring system  Setup workflow  Setup error  Margin expansion
FundProject:北京市自然科学基金(1202009,1184014,7172048)
Author NameAffiliationE-mail
Li Junyu Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Yu Songmao Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Zhou Shun Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Wu Hao Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Gong Jian Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Yang Jingxian Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Yue Haizhen Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China  
Li Tingting The Fifth Medical Center of PLA General Hospital, Beijing 100039, China  
Du Yi Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing), Department of Radiation Oncology, Peking University Cancer Hospital&Institute, Beijing 100142, China yi.du@hotmail.com 
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Abstract::
      Objective To build patient setup workflow based on the optical surface monitoring system (OSMS) in postoperative radiotherapy for breast cancer, and compare the setup accuracy and PTV margin between OSMS based setup and conventional skin marker based method. Methods The setup data of 20 cases of postoperative radiotherapy for breast cancer were retrospectively analyzed and divided into two groups:OSMS setup group and conventional skin marker setup group with 10 patients in each group. All CBCT rigid registration values in six dimensions (x, y, z, Rtn, Pitch, Roll) were obtained, and the absolute value and distribution of errors were statistically analyzed by single sample t-test and χ2-test respectively. Finally, the CTV-PTV margins were compared using the extension formula. Results The mean values in OSMS setup group and conventional skin marker setup group in sixdirections were 0.18 and 0.18 cm, 0.12 and 0.13 cm,0.13 and 0.23 cm, 0.55° and 0.74°, 0.63° and 0.99°, 0.67° and 0.68°, respectively, while the standard deviations were 0.13 and 0.12 cm, 0.09 and 0.09 cm, 0.11 and 0.16 cm, 0.37° and 0.55°, 0.53° and 0.65°, 0.42° and 0.55°, respectively. The setup error differed in both z and Pitch directions(t=3.53,2.98,P<0.05), while the error distribution rate difference was statistically significant between two groups in z direction(χ2=11.090,P<0.05). The CTV-PTV margins in OSMS setup group and conventional skin marker setup group were 0.28 and 0.26 cm, 0.21 and 0.20 cm, 0.24 and 0.35 cm, respectively. Conclusions The proposed OSMS-based patient setup work flow is better than the conventional skin marker based method in setup accuracy, with significant setup error differences in z and Pitch directions. The proposed OSMS workflow is of potential clinical benefit.
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