| Dai Yingchu,Lu Jiade,Zhou Guangming.Progress on the fundamental biological studies for tumor therapy with heavy particles[J].Chinese Journal of Radiological Medicine and Protection,2020,40(3):247-252 |
| Progress on the fundamental biological studies for tumor therapy with heavy particles |
| Received:November 06, 2019 |
| DOI：10.3760/cma.j.issn.0254-5098.2020.03.016 |
| KeyWords:Heavy ion Tumor radiotherapy Relative biological effectiveness Oxygen enhancement ratio |
| FundProject:国家重点研发计划（2018YFC0115705）；国家自然科学基金（11335011） |
| Author Name | Affiliation | E-mail | | Dai Yingchu | School of Radiation Medicine and Protection, Medical College of Soochow University, State Key Laboratory of Radiation Medicine and Protection, Innovation Center for Radiological Medicine of Jiangsu Higher Education Institutions, Suzhou 215123, China | | | Lu Jiade | Shanghai Heavy Ion and Proton Center, Shanghai 201321, China | | | Zhou Guangming | School of Radiation Medicine and Protection, Medical College of Soochow University, State Key Laboratory of Radiation Medicine and Protection, Innovation Center for Radiological Medicine of Jiangsu Higher Education Institutions, Suzhou 215123, China | gmzhou@suda.edu.cn |
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| Abstract:: |
| Due to its unique physical and biological advantages, heavy ion beam has great advantages as tumor radiotherapy ray. Tumor therapy with heavy particles has achieved outstanding clinical outcome and is of the potential to become the most advanced radiotherapy in this century. Fundamental studies on the biological effects are of significance in providing theoretical principle and optimizing beam quality for tumor therapy with heavy particles. Meanwhile, the application of new techniques such as FLASH and GRID in tumor therapy with heavy particles requires fundamental biological studies as well, especially in improving clinical efficacy and security. In this article, we review the progress on the fundamental biological studies for tumor therapy with heavy particles and arouse discussion on the issues necessary for further elucidation. |
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