| Tian Xuelei,Lu Xue,Feng Jiangbin,et al.Influence factors of nucleoplasmic bridge frequencies in the peripheral blood lymphocytes of radiation workers[J].Chinese Journal of Radiological Medicine and Protection,2020,40(2):94-98 |
| Influence factors of nucleoplasmic bridge frequencies in the peripheral blood lymphocytes of radiation workers |
| Received:April 09, 2019 |
| DOI：10.3760/cma.j.issn.0254-5098.2020.02.004 |
| KeyWords:Nucleoplasmic bridges Radiation worker Influence factors Ionizing radiation |
| FundProject:国家自然科学基金（81573081） |
| Author Name | Affiliation | E-mail | | Tian Xuelei | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Lu Xue | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Feng Jiangbin | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Lyu Yumin | Laboratory of Toxicology, Henan Institution of Occupational Medicine, Zhengzhou 450052, China | | | Tian Mei | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | | | Liu Qingjie | Key Laboratory of Radiological Protection and Nuclear Emergency, China CDC, National Institute for Radiological Protection, Chinese Center for Disease Control and Prevention, Beijing 100088, China | liuqingjie@nirp.chinacdc.cn |
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| Abstract:: |
| Objective To study the effects of sex, age, length of service, type of work and annual effective radiation dose on nucleoplasmic bridge (NPB) in the peripheral blood lymphocytes of radiation workers. Methods The peripheral blood samples of 100 radiation workers in Henan province were collected and the NPB in peripheral blood lymphocytes were measured by CBMN assay. The frequencies of NPB formation and NPB-containing cells were calculated, and the effects of various factors on NPB incidence were analyzed statistically. Results The NPB frequency in radiation workers was higher than that in healthy people (Z=-8.123, P<0.01). Except for sex, the factors of age, length of service, type of work and annual effective dose had significant influences on NPB (χ2=7.202-45.571,P<0.05). Conclusions NPB reflects the effect of low-dose long-term chronic irradiation on the occupational radiation workers. |
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