| Li Chengqiang,Tao Cheng,Chen Jinhu,Zhu Jian,Lu Jie,Bai Tong,Zhang Guifang,Liu Tonghai,Yin Yong.The plan quality and delivery efficiency of intensity modulated radiotherapy on a new designed linac for left side breast cancer[J].Chinese Journal of Radiological Medicine and Protection,2019,39(8):614-618 |
| The plan quality and delivery efficiency of intensity modulated radiotherapy on a new designed linac for left side breast cancer |
| Received:March 13, 2019 |
| DOI：10.3760/cma.j.issn.0254-5098.2019.08.010 |
| KeyWords:Breast cancer Dual layer MLC Intensity modulated radiotherapy Flatten filter free Segment area |
| FundProject:国家自然科学基金（81472811，81671785）；国家重点研发计划数字诊疗装备研发重点专项临床验证评价子课题（2016YFC0105106）；山东省重点研发计划项目（2018GSF118006）；山东省自然科学基金（ZR2016HQ09） |
| Author Name | Affiliation | E-mail | | Li Chengqiang | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Tao Cheng | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Chen Jinhu | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Zhu Jian | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Lu Jie | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Bai Tong | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Zhang Guifang | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Liu Tonghai | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | | | Yin Yong | Department of Radiation Oncology Physics, Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China | yongyinsd@163.com |
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| Abstract:: |
| Objective To analyze the dosimetric and delivery efficiency differences between IMRT plans based on Halcyon and Trilogy Accelerator for left side breast cancer. Methods A total of 10 patients with left side breast cancer based on the Trilogy platform were retrospectively analyzed. For each patient,plan based on Halcyon was redesigned using Eclipse Version 15.1 TPS. In order to evaluate plan quality, dose coverage of target and dose to organs at risk, monitor unit efficiency, segment size and delivery time were compared. Results Halcyon treatment platform could meet the clinical objective. Dose distribution of the target volume had no significant difference with the Trilogy plans (P>0.05). Volumes receiving 10 Gy,20 Gy and Dmean of the left lung were significantly reduced(Z=-2.22--1.78, P<0.05). V5 of heart for Halcyon and Trilogy was(27.80±7.66)% and (23.18±8.19)%, respectively(Z=-0.71, P<0.05), while Dmean was (7.03±1.8)Gy and(7.11±2.40)Gy, respectively(P>0.05). Halcyon increased the monitor unit from 1 526.2±227.7 by Trilogy to 1 770.5±383.9(Z=-0.71, P<0.05), but decreased the delivery time from (12.38±1.49)min by Trilogy to (3.01±0.28)min(Z=-3.42, P<0.05). Conclusion Halcyon treatment platform can meet the clinical requirements, reduce dose to normal tissue with high delivery efficiency. |
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