| Huang Xurui,Huang Haiwei.Advances in the mechanism of inflammatory response to radiation-induced brain injury[J].Chinese Journal of Radiological Medicine and Protection,2018,38(11):870-873 |
| Advances in the mechanism of inflammatory response to radiation-induced brain injury |
| Received:April 15, 2018 |
| DOI：10.3760/cma.j.issn.0254-5098.2018.11.014 |
| KeyWords:Radiation-induced brain injury Microglia Reactive oxygen species Inflammatory mediators Leukocytes |
| FundProject:广东省科技计划项目（2016A020215040） |
| Author Name | Affiliation | | Huang Xurui | Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China | | Huang Haiwei | Department of Neurology, National Key Clinical Department and Key Discipline of Neurology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China |
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| Abstract:: |
| The mechanisms of radiation-induced brain injury (RBI) remain unclear. Currently a number of studies suggest that inflammatory response may play an important role in RBI. The production of reactive oxygen species, the release of inflammatory mediators, the interactions between neurons, glial cells, and pericytes, and the recruitment of peripheral leukocytes all contribute to the development of radiation-induced brain injury. This article reviews the research progress of the inflammatory response mechanism of radiation-induced brain injury. |
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