Liu Meiyue,Liu Jianping,Hu Wanning,et al.Application of combined body position fixation in radiation therapy of lung cancer[J].Chinese Journal of Radiological Medicine and Protection,2018,38(11):830-835
Application of combined body position fixation in radiation therapy of lung cancer
Received:June 15, 2018  
DOI:10.3760/cma.j.issn.0254-5098.2018.11.006
KeyWords:Lung cancer  Polystyrene foam  Thermoplastic film  Set-up error  Target volume
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Author NameAffiliationE-mail
Liu Meiyue Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Liu Jianping Department of Radiation Therapy Center, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan 063001, China, China  
Hu Wanning Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Yang Haifang Department of Radiation Therapy Center, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan 063001, China, China  
Yao Weinan Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Jia Jinghao Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Gao Peng Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Sun Lu Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Zhang Lixin Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China  
Sun Guogui Department of Chemoradiotherapy Ⅱ, The Affiliated People's Hospital, North China University of Science and Technology, Tangshan, 063001, China guogui_sun2013@163.com 
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Abstract::
      Objective To explore the CTV to PTV external expansion boundary and the effect of the dose of normal lung tissue under different fixed modes by a comparative analysis of combined body position and thermoplastic film fixed set-up error of radiation therapy for lung cancer. Methods From October 2016 to March 2018, the patients who received chest radiology at the Tangshan people's hospital were enrolled as subjects retrospectively divided into two groups, including 50 patients with lung cancer radiotherapy with combined body position fixation, and 40 patients with lung cancer with thermoplastic film fixation. The two groups of patients drew the target areas in accordance with the unified standard, and the set-up error of left and right, up and down, front and rear (x, y, z axis) were recorded respectively after 1 time/week cone CT(CBCT) matched with the planned CT image and analyzed by ttest. According to the MPTV=2.5Σ+0.7δ, CTV to PTV external expansion boundary in the combined body position group were calculated. And the V5V20 and V30 of two groups of patients were calculated and analyzed by TPS system. Results The set-up error of the combined body position group and thermoplastic film group were respectively (1.00±0.58) mm and (3.28±0.43) mm on the x axis, (1.42±0.28) mm on the y axis and (4.03±0.41) mm, (1.06±0.44) mm and (3.18±0.34) mm on the z axis. The set-up errors of the two groups were statistically significant on x, y and z axis(t=-20.740, -35.596, -25.015,P<0.05). There was no significant difference in set-up errors between the central and peripheral lung cancer patients and between left and right lung cancer patients(P>0.05).Through the MPTV=2.5Σ+0.7δ, CTV to PTV external expansion boundary in the combined body position fixation group was 2.906, 3.746 and 2.958 mm on x, y and z axis respectively. The comparison between group A and B showed that the mean values of V5, V20 and V30 in group B were reduced by 1.5%, 3.1% and 4.8% respectively compared with group A. Conclusions The combined body position technique can improve the accuracy of lung cancer patients after radiation therapy,and further reduce the boundary of CTV to PTV, which is of certain value to reduce the occurrence of radiation pneumonitis.
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