Wang Weiwei,Sheng Yinxiangzi,Huang Zhijie,Kambiz Shahnazi.EBT3 and EDR2 film dosimetry for scanning carbon ion beams[J].Chinese Journal of Radiological Medicine and Protection,2018,38(9):705-709
EBT3 and EDR2 film dosimetry for scanning carbon ion beams
Received:February 08, 2018  
DOI:10.3760/cma.j.issn.0254-5098.2018.09.013
KeyWords:EBT3  EDR2  Film dosimetry  Carbon ion therapy
FundProject:上海市科学技术委员会重点支撑项目(15411950105);上海市卫生与计划生育委员会青年基金项目(20174Y0134)
Author NameAffiliationE-mail
Wang Weiwei Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai 201321, China  
Sheng Yinxiangzi Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai 201321, China  
Huang Zhijie Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai 201321, China zhijie.huang@sphic.org.cn 
Kambiz Shahnazi Department of Medical Physics, Shanghai Proton and Heavy Ion Center, Shanghai 201321, China  
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Abstract::
      Objective To investigate EBT3 and EDR2 film responses to different linear energy transfers (LETs) and doses from carbon ion beams. Methods EBT3 and EDR2 films were calibrated by two methods. In the first method, films were placed at the same depth within a phantom and irradiated by beams with different parameters such as beam energy. In the second method, films were separately placed at different depths in a phantom and irradiated by the same beams. These methods were used to irradiate films with ions of different LETs. Results For EBT3 film, the dose calibration curves correlated with different LETs appeared to be typical hyperbolic curves with a maximum difference between the curves of ±17% (1σ). Meanwhile, the shape of the dose calibration curves for EDR2 film appeared to be linear. The values along all these curves were within ±27.4% (1σ) of the value for the average curve. The dose responses of both films were inversely proportional to LETs. The sensitivity of EBT3 film was inversely proportional to the dose, while the sensitivity of EDR2 film showed no relationship with the dose. Conclusions Influenced by the dual factor of LET and dose, the application of EBT3 film was limited in carbon ion. However, without no dose dependence, EDR2 film could be used to measure dose distributions created by single LET carbon ion beam.
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