Sun Haitao,Yao Lihong,Wang Junjie,Zhou Fugen,Jiang Yuliang,Ji Zhe,Liu Bo,Guo Fuxin,Peng Ran,Fan Jinghong.3D-printing non-coplanar template assisted 125Ⅰ seed implantation for pelvic tumor: individual template design method[J].Chinese Journal of Radiological Medicine and Protection,2017,37(7):485-489
3D-printing non-coplanar template assisted 125Ⅰ seed implantation for pelvic tumor: individual template design method
Received:March 22, 2017  
DOI:10.3760/cma.j.issn.0254-5098.2017.07.002
KeyWords:3D-printing  Radioactive seed implantation  Personalized non-coplanar template  Dosimetry  Pelvic tumor
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Author NameAffiliationE-mail
Sun Haitao Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Yao Lihong Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Wang Junjie Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China junjiewang_edu@sina.cn 
Zhou Fugen Image Processing Center, Beihang University, Beijing 100191, China  
Jiang Yuliang Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Ji Zhe Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Liu Bo Image Processing Center, Beihang University, Beijing 100191, China  
Guo Fuxin Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Peng Ran Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
Fan Jinghong Department of Radiation Oncology, Peking University Third Hospital, Beijing 100191, China  
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Abstract::
      Objective To compare the dosimetric data between preoperative plans and postoperative verification in computed tomography (CT)-guided and 3D-printing non-coplanar template-assisted 125Ⅰ seed implantation for pelvic tumor, and to explore the feasibility and accuracy of the personalized template designmethod. Methods A total of 51 patients registered from Dec 2015 to Dec 2016 who were applied with 3D-printing guided template assisted radioactive seed implantations in the hospital were included in this study.A prescribed dose of 110-160 Gy was adopted. 3D-printing templates were designed and produced for 51 cases. The dosimetric parameters: D90, minimum peripheral dose (mPD), V100, V150, V200, conformal index (CI), external index (EI), and homogeneity index (HI) were compared between pre-and post-plans. Results 51 cases' templates were in place well during the operations. Compared with the preoperative planning, the postoperative D90, V100, V150, V200, CI, EI and HI differences had no statistical difference (P>0.05); mPD is larger than before (t=-2.96,P<0.05). Conclusions The main dosimetric parameters of postoperative verification were consistent well with the preoperative planning and have good accuracy, which could meet the clinical requirements.
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