Pang Tingtian,Yang Bo,Liu Xia,Liu Nan,Dong Tingting,Qiu Jie.Feasibility study on the application of accelerator MV CBCT images in adaptive radiation therapy[J].Chinese Journal of Radiological Medicine and Protection,2017,37(5):359-362
Feasibility study on the application of accelerator MV CBCT images in adaptive radiation therapy
Received:November 08, 2016  
DOI:10.3760/cma.j.issn.0254-5098.2017.05.007
KeyWords:Adaptive radiation therapy  Megavoltage cone beam CT  Image value to density table (IVDT)  Dose distribution
FundProject:National science and technology basic work (2014YF211000)
Author NameAffiliationE-mail
Pang Tingtian Department of Radiotherapy, Peking Union Medical College Hospital, Beijing 100730, China  
Yang Bo Department of Radiotherapy, Peking Union Medical College Hospital, Beijing 100730, China  
Liu Xia Department of Radiotherapy, Peking Union Medical College Hospital, Beijing 100730, China  
Liu Nan Department of Radiotherapy, Peking Union Medical College Hospital, Beijing 100730, China  
Dong Tingting Department of Radiotherapy, Peking Union Medical College Hospital, Beijing 100730, China  
Qiu Jie Department of Radiotherapy, Peking Union Medical College Hospital, Beijing 100730, China 13501015586@139.com 
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Abstract::
      Objective To investigate whether the accelerator image beam line (IBL) full scan and extend field of view(EFOV) scan mode megavoltage cone beam CT(MV CBCT) images can be used for dose calculation in adaptive radiotherapy.Methods The large aperture CT and MV CBCT were used to scan the CIRS 062M electron density modules, the CT value was established to electron density curves in the Pinnacle treatment planning system. Also, CT and MV CBCT were used to scan the head and neck, chest, abdomen and pelvis phantom. The intensity modulated radiotherapy(IMRT) plans were made with CT images and transplanted to MV CBCT images. The dose of targets and organs with their electron density curves was calculated, and two type IMRT plans with different CT images were compared. Results The dose distribution of head and neck phantom was acceptable, compared with the reference plan, the difference was within 3%. The dose distribution of chest and pelvis was significantly reduced from reference plans, and the difference was 5% and 10% separately. This difference was beyond the scope of clinical acceptance. Conclusions MV CBCT images of accelerator IBL full scan mode in patients with head and neck site scan could be used for dose calculation in adaptive radiotherapy, chest and pelvic sites in EFOV mode scanning MV CBCT images could only be used for image guidance.
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