Tong Ying,Yin Yong,Chen Jinhu,Gong Guanzhong,Fu Lu,Gu Jiabing,Cheng Pinjing.Setup errors for the tumors in different parts of body with TomoTherapy[J].Chinese Journal of Radiological Medicine and Protection,2017,37(5):352-358
Setup errors for the tumors in different parts of body with TomoTherapy
Received:November 21, 2016  
DOI:10.3760/cma.j.issn.0254-5098.2017.05.006
KeyWords:TomoTherapy  Megavoltage CT scan  Setup errors
FundProject:国家自然科学基金(81472811,81301936,81272699);山东省科技发展计划项目(2014GGC03038)
Author NameAffiliationE-mail
Tong Ying School of Nuclear Science and Technology, University of South China, Hengyang 421001, China
Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University 
 
Yin Yong Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China  
Chen Jinhu Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China  
Gong Guanzhong Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China  
Fu Lu Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China  
Gu Jiabing Radiation Physics Department of Shandong Cancer Hospital Affiliated to Shandong University, Jinan 250117, China  
Cheng Pinjing School of Nuclear Science and Technology, University of South China, Hengyang 421001, China nhuchpj@aliyun.com 
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Abstract::
      Objective To investigate the distribution rules of setup errors in different locations for tomotherapy.Methods 151 patients induding 53 head and neck tumors, 45 thoracic tumors, 20 abdominal tumors, and 33 pelvic tumors, who accepted tomotherapy were retrospectively analyzed in this study. The planning CT images of patients were obtained in simulation, and all patients underwent megavoltage CT (MVCT) scan before radiotherapy. And the setup errors were calculated by rigid registering MVCT images to planning CT images, and setup errors on +x(left), -x(right), +y(in), -y(out), +z(ventral), -z (dorsal)axes were analyzed respectively. Results A total of 3 281 MVCT scans were performed on 151 patients, The setup errors on +x (left), -x(right), +y(in), -y(out), +z (ventral), -z (dorsal)axes were (1.61±1.21), (1.76±2.11), (2.26±1.74), (1.83±1.47), (3.24±1.76) and (1.75±1.61)mm for head and neck tumors; (2.43±1.88), (2.55±1.92), (3.06±2.64), (3.90±2.91), (6.71±3.46) and (2.64±2.77)mm for thoracic tumors; (3.67±3.06), (2.37±1.77), (3.18±1.96), (3.98±3.01), (6.74±3.25) and (1.92±2.00)mm for abdominal tumors; (2.92±2.13), (2.17±1.68), (3.50±2.61), (3.72±2.66), (7.18±3.43) and (1.92±1.61)mm for pelvic tumors, respectively. The setup errors were different between +z and -z with statistically significant in all tumors (t=-4.119、-5.033、-3.763、-5.057,P<0.05). The setup errors on +z direction of patients immobilized with thermoplastic mask were smaller than those immobilized with vacuum cushions for thoracic tumors (t=-2.357,P<0.05). Conclusions The setup errors of head and neck tumors are less than other parts tumor in tomotherapy. The patients immobilized with thermoplastic mask can reduce the setup errors for thoracic tumors. The heterogeneity of setup errors on ventral-dorsal directions for the all parts of tumors should not be ignored.
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