| Yang Shangwen,Shao Mingran,Yang Xianfeng,Hu Anning,Wang Zhong,Jiang Hui,Zhu Bin,Zhang Bing,Xin Xiaoyan.A feasibility study on “Tri-Low” technology in combination with iterative model reconstruction(IMR) algorithm in CT angiography(CTA) of the head-and-neck vessels[J].Chinese Journal of Radiological Medicine and Protection,2017,37(1):62-67 |
| A feasibility study on “Tri-Low” technology in combination with iterative model reconstruction(IMR) algorithm in CT angiography(CTA) of the head-and-neck vessels |
| Received:August 04, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2017.01.012 |
| KeyWords:Angiography Tomography, X-ray computed Radiation dose Iterative reconstruction |
| FundProject:江苏省卫生厅青年科研课题（Q201410） |
| Author Name | Affiliation | | Yang Shangwen | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Shao Mingran | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Yang Xianfeng | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Hu Anning | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Wang Zhong | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Jiang Hui | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Zhu Bin | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Zhang Bing | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China | | Xin Xiaoyan | Deparment of Radiology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, 210008, China |
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| Abstract:: |
| Objective To evaluate the feasibility of low-tube-voltage,low injection rate,low contrast agent dosage in combination with iterative model reconstruction(IMR) algorithm in CT angiography(CTA) of the head-and-neck vessels.Methods Sixty patients who underwent CT angiography of the head-and-neck vessels were randomly divided into groups A and B with 30 cases in each group. Patients in group A received a conventional scan with 120 kVp and filterback projected(FBP) reconstruction. Patients in group B received a low-dose scan with 80 kVp, and image reconstruction with FBP(group B1) and IMR(group B2) algorithm. The contrast agent protocol were as follows:the injection time in all patients was 10s, the injection rate was 4.5-5.5 ml/s in group A while 3.5-4.0 ml/s in group B. The CT values of artery, image noise, signal to noise ratio(SNR) and contrast to noise ratio(CNR) were measured and compared among three groups with One-way ANOVA analysis. Image quality was evaluated by two radiologists with five scale method, and compared with Kruskal-Wallis test. The CT dose index volume (CTDIvol) and dose length product (DLP) were recorded and compared between groups with two independent samples t-test. Results The image quality scores of groups A, B1and B2 were 3-5, 2-4 and 3-5, respectively.Image quality of twelve patients in group B1 couldn't meet the diagnostic requirements but none in group A and B2.The objective image parameters SNR and CNR for group B2 were equal to group A(P>0.05), while those for group B1 were lower than group A(t=13.39, 9.45,P<0.05) and group B2(t=-12.14, -9.96, P<0.05). CTDIvol and DLP for group B were separately 80.9%, 81.3% lower than those of group A(t=39.1, 32.2, P<0.05). The injection rate and contrast agent volume for group B were separately 22.0%, 22.1% lower than those of group A(t=20.8, 20.8, P<0.01).Conclusions It is feasible in CT angiography of the head-and-neck vessels with lower tube-voltage, lower injection rate, lower contrast agent dose and combining with iterative model reconstruction algorithm. This protocol can reduce the radiation dose by 81.3% while maintaining image quality.Trial registration Chinese clinical trial registry,ChiCTR-BOC-16010060. |
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