| Liao Xiongfei,Li Churong,Li Jie,Chen Yazheng,Yuan Ke,Wang Pei.Comparative analysis of effective dose between helical tomotherapy and multi-ISO radiotherapy in craniospinal irradiation[J].Chinese Journal of Radiological Medicine and Protection,2017,37(1):45-49 |
| Comparative analysis of effective dose between helical tomotherapy and multi-ISO radiotherapy in craniospinal irradiation |
| Received:August 16, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2017.01.009 |
| KeyWords:Craniospinal irradiation Helical tomotherapy Multi-ISO radiotherapy Effective dose |
| FundProject: |
| Author Name | Affiliation | E-mail | | Liao Xiongfei | Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China | | | Li Churong | Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China | | | Li Jie | Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China | | | Chen Yazheng | Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China | | | Yuan Ke | Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China | | | Wang Pei | Department of Radiotherapy, Sichuan Cancer Hospital, Chengdu 610041, China | dengwangpei@163.com |
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| Abstract:: |
| Objective To compare the effective dose deposited in patients between helical tomotherapy (HT) and multi-ISO radiotherapy (M-ISO) in carniospinal irradiation(CSI).Methods Nine children with craniospinal irradiation were selected. For these patients, new plans were designed with HT and M-ISO centers planning method on the treatment planning system (TPS). The effective dose of the nine patients from 18 treatment plans were calculated,and the difference of the effective dose between HT and M-ISO was compared using paired t-test. Results The plans designed in two groups were both satisfied all clinical requirements. For the planning target volume (PTV), no statistically significant difference was found in D95% between two groups (P>0.05), while D98%, D2% and homogeneity index (HI) in HT group were superior to M-ISO group (t=2.762, 2.413, 4.563, P<0.05), D50%, Dmean and CI in M-ISO group were superior to HT group (t=5.259, 3.685, 7.815,P<0.05). HT and M-ISO had different advantages in the protection of the OARs. The effective dose of patients in M-ISO group was superior to HT group (t=5.921,P<0.05). Conclusions HT and M-ISO have different advantages in CSI. The low dose area has greater influence on the effective dose in HT group compared to M-ISO group. The low dose area should be concerned while designing the treatment planning for CSI. |
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