He Changjiu,Hu Shibei,Xu Guohui,Li Hailie,Liu Fang,Feng Bin,Zhou Peng.Application of automatic tube current modulation combined with iterative reconstruction algorithm in low-dose CT pulmonary angiography[J].Chinese Journal of Radiological Medicine and Protection,2016,36(11):857-861
Application of automatic tube current modulation combined with iterative reconstruction algorithm in low-dose CT pulmonary angiography
Received:July 20, 2016  
DOI:10.3760/cma.j.issn.0254-5098.2016.11.012
KeyWords:Computed tomography pulmonary angiography  Radiation dose  Iterative reconstruction  Automatic tube current modulation
FundProject:四川省科技计划项目(2014JY0240)
Author NameAffiliationE-mail
He Changjiu Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Hu Shibei Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Xu Guohui Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Li Hailie Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Liu Fang Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Feng Bin Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China  
Zhou Peng Sichuan Cancer Hospital & Institute, Sichuan Cancer Center, School of Medicine, University of Electronic Science and Technology of China, Chengdu 610041, China penghyzhou@126.com 
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Abstract::
      Objective To explore the application value of automatic tube current modulation combined with iterative reconstruction algorithm (idose4) in low-dose computed tomography pulmonary angiography (CTPA). Methods A total of 80 patients with CTPA collected continuously were randomly divided into control group (n=40, 80 kV, 180 mAs) and experimental group (n=40, 80 kV, automatic tube current modulation). The data sets of control group were reconstructed with filtered-back-projection algorithm (group A), and the data sets of experimental group were reconstructed with filtered-back-projection algorithm (group B) and iterative reconstruction algorithm (group C). Subjective score, mean CT values of pulmonary artery, image noise, signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) were recorded. Effective dose (E) was compared. Results The E of experimental group was decreased by 36.8% compared to control group (t=-3.998, P<0.05). The subjective scores of 3 groups were more than 3 which could meet the requirements of clinical diagnosis, and there was no statistically significant difference (P>0.05). There was statistically significant difference for the SNR, CNR and image noise of 3 groups (F=10.411, 7.630, 13.021, P<0.05), but no statistically significant difference for the mean CT value of pulmonary artery (P>0.05). Conclusions Using automatic tube current modulation combined with iterative reconstruction algorithm in low-dose CTPA could meet the requirements of image quality, and reduce the radiation dose to a certain extent.
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