| Wang Aimin,Cao Guoquan,Pan Kehua,et al.The application of low concentration of contrast agent combined with low tube voltage in CT pulmonary angiography[J].Chinese Journal of Radiological Medicine and Protection,2016,36(9):707-711 |
| The application of low concentration of contrast agent combined with low tube voltage in CT pulmonary angiography |
| Received:March 23, 2016 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.09.016 |
| KeyWords:Pulmonary angiography Tomography,X-ray computed Contrast media Tube voltage |
| FundProject:国家“十二五”支撑计划项目（2011BA11B17）；浙江省卫计委科技计划项目（2015KYB247） |
| Author Name | Affiliation | E-mail | | Wang Aimin | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Cao Guoquan | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Pan Kehua | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | 535260767@qq.com | | Wang Zhenzhang | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Guo Xianzhong | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Wang Liangxing | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Huang Xiaoying | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Liu Jinjin | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | | | Zhao Liang | Department of Radiology, First Affiliated Hospital, Wenzhou Medical University, Wenzhou 325015, China | |
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| Abstract:: |
| Objective To evaluate the feasibility and value of using dilute iodine contrast agent combined with low tube voltage in CT pulmonary angiography (CTPA). Methods A total of 60 patients with clinically suspected pulmonary embolism were enrolled in this prospective study. All of them were divided into three groups(n=20) using a table of random numbers method, and then underwent CTPA (group A:120 kV, auto mA, 350 mgI/ml,FBP algorithm; group B:100 kV, auto mA,280 mgI/ml,AIDR3D standard algorithm; group C:80 kV, auto mA,245 mgI/ml,AIDR3D strong algorithm).In these three groups, CT volume dose index (CTDIvol), pulmonary artery enhanced CT values, background noise, signal to noise ratio (SNR), and the contrast to noise ratio (CNR) in each group were calculated. All of the data and the subjective scores of image quality for each group were compared. Results The average CT value in group A was significantly lower than that in group C (F=2.65, P<0.05). However, there was no significant difference between other groups (P>0.05). The noise in group A was much higher than that in groups B and C(F=16.38, P<0.001),there was no statistically significant difference between group B and group C (P>0.05). Compared with groups B and C, SNR and CNR were lower in group A with statistically significant differences (F=17.17, 19.13, P<0.001). There was no statistical difference of the CTDIvol and image quality scores among three groups. Conclusions In CTPA, the application of dilute iodine contrast agent combined with low tube voltage and AIDR3D reconstruction algorithm for all except obese patients can decrease radiation dose while meeting the diagnostic requirements of image quality, which has a good clinical application value. Trial registration Peking Union Medical College Hospital, PUMCH-PULMONARY DISEASES 2011BA11B17. |
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