| Li Simei,Wang Yadi,Chen Jianping,Zhang Fuli,Chen Diandian,Lu Na.Margins of planning target volume in cervix cancer with tomotherapy[J].Chinese Journal of Radiological Medicine and Protection,2016,36(3):216-219 |
| Margins of planning target volume in cervix cancer with tomotherapy |
| Received:October 29, 2015 |
| DOI：10.3760/cma.j.issn.0254-5098.2016.03.011 |
| KeyWords:Cervical cancer Tomotherapy Image guided radiation therapy (IGRT) Setup errors Margin of planning target volume |
| FundProject:首都卫生发展科研专项(2011-5021-05) |
| Author Name | Affiliation | E-mail | | Li Simei | Postgraduate Insttitute of the Southern Medical University, Guangzhou 510515, China | | | Wang Yadi | Postgraduate Insttitute of the Southern Medical University, Guangzhou 510515, China | wangyadi@hotmail.com | | Chen Jianping | Department of Radiation Oncology, General Hospital of Beijing Military Region, Beijing 100700, China | | | Zhang Fuli | Department of Radiation Oncology, General Hospital of Beijing Military Region, Beijing 100700, China | | | Chen Diandian | Department of Radiation Oncology, General Hospital of Beijing Military Region, Beijing 100700, China | | | Lu Na | Department of Radiation Oncology, General Hospital of Beijing Military Region, Beijing 100700, China | |
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| Abstract:: |
| Objective To determine the margins of planning target volume (MPTV) in primary cervical cancer patients with tomotherapy and evaluate the importance of automatic registration(AR) plus manual registration. Methods The setup errors of 29 primary cervical cancer patients receiving external radiation from June 2012 to Dec 2014 were measured by megavoltage computed tomography (MVCT), which were performed at least two times weekly before treatment and were registered with the planning CT. The setup errors between automatic registration and total shift(TS) including both AR and manual registration were compared MPTV was calculated. Results Setup errors were collecte from 443 sets of MVCT in 29 patients. AR and total shift (TS) values in the x, y, z directions and rotation angle were (-0.9±2.3), (0.0±3.1), (1.0±2.6) mm, 0.2°±0.8° and (-0.8±1.8), (-0.4±3.4), (1.4±2.5) mm, 0.1°±0.5°, respectively. There were statistically significant differences between the two groups in all directions except for the x axis (t=5.1, -5.2, 3.2, P<0.05). MPTV were 4.6, 5.7, 3.3 mm in the x, y, z directions, respectively. Conclusions Manual registration is necessary after automatic registration in cervical cancer patients with tomotherapy. For patients with cervical cancer treated by tomotherapy, planning target volume MPTV parameters are suggested to be 5, 6, 4 mm in the x, y, z directions. |
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