Zhuang Tingting,Lin Baihan,Li Dongsheng,Wu Lili.Dosimetric comparison of stereotactic body radiation therapy plans for spine metastasis using flattening filter free and flattening filter modes[J].Chinese Journal of Radiological Medicine and Protection,2016,36(1):63-66
Dosimetric comparison of stereotactic body radiation therapy plans for spine metastasis using flattening filter free and flattening filter modes
Received:September 02, 2015  
DOI:10.3760/cma.j.issn.0254-5098.2016.01.012
KeyWords:Spine metastasis  Stereotactic body radiation therapy  Flattening filter free  Dosimetry
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Author NameAffiliationE-mail
Zhuang Tingting Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515031, China  
Lin Baihan Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515031, China  
Li Dongsheng Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515031, China  
Wu Lili Department of Radiation Oncology, Cancer Hospital of Shantou University Medical College, Shantou 515031, China lily_wu_ph@qq.com 
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Abstract::
      Objective To compare the dosimetric difference of stereotactic body radiation therapy (SBRT) plans for spine metastasis using 6 MV X-ray flattening filter free (FFF) and flattening filter (FF) modes. Methods A total of nine previously treated patients with a total of twelve spine metastasis were retrospectively included and replanned using FFF-SBRT and FF-SBRT, respectively. The dose-volume histograms (DVH), target conformity index (CI), monitor unites (MUs) and treatment time of target volume, organs at risk and normal tissues were compared between the plans. Results Both FFF-SBRT and FF-SBRT met the clinical objectives. Dose distribution of target volume, organs at risk and normal tissues were similar. MUs of the FFF-SBRT were significantly higher than that of FF-SBRT (t=-5.20, P<0.01), while the treatment time was almost half of the latter (t=17.27, P<0.01). ConclusionsTwo plan modes are both clinically acceptable. FFF-SBRT plans are delivered in less time and with better efficiency. Trial registration Chinese clinical trial registry, ChiCTR-TRC-14004281.
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