| Wang Feng,Zhao Wei,Zhao Qichao,et al.Analysis of patient radiation dose from nuclear medicine examinations[J].Chinese Journal of Radiological Medicine and Protection,2015,35(9):705-708 |
| Analysis of patient radiation dose from nuclear medicine examinations |
| Received:March 03, 2015 |
| DOI：10.3760/cma.j.issn.0254-5098.2015.09.017 |
| KeyWords:PET-CT ECT Radiation Absorbed dose Nuclear medicine |
| FundProject:国家自然科学基金(81371592,81172083);北京市自然科学基金(7132040) |
| Author Name | Affiliation | E-mail | | Wang Feng | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | | | Zhao Wei | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | | | Zhao Qichao | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | | | Zhang Yan | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | | | Chen Puyun | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | | | Fan Yang | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | | | Yang Zhi | Key Laboratory of Carcinogenesis and Translational Research, Ministry of Education, Department of Nuclear Medicine, Peking University Cancer Hospital & Institute, Beijing 100036, China | pekyz@163.com |
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| Abstract:: |
| Objective To measure and analyze the radiation dose for patients undergoing nuclear medicine examination, and to characterize radiation exposure of patients by using the estimated effective dose. Methods Patients undergoing nuclear medicine examinations were classified and the radiation doses from radiopharmaceuticals to patients were measured and calculated. Meanwhile, radiation exposure from computed tomography (CT) procedure was calculated on the basis of CT protocols and patients' information. The effective doses to patient from both the radiopharmaceutical and CT scan radiation were calculated and the factors influencing patient radiation doses were analyzed. Results For the patients undergoing positron emission tomography-computed tomography (PET-CT) examination, the average effective doses from positron radiopharmaceutical 18F-fluorodeoxyglucose (18F-FDG), 18F-fluoro-l-thymidine (18F-FLT), 11C-choline,11C-methylmethionine (11C-MET) and 11C-acetate (11C-Ac) were (5.06±0.73), (4.74±1.29), (1.71±0.05), (3.18±0.69) and (1.08±0.19) mSv, respectively. CT scan caused average effective dose was (8.80±0.58) mSv. If a full diagnostic CT investigation was performed, the effective dose might be up to 27 mSv. Whereas for emission computed tomography (ECT) examinations, the average effective dose to the patients irradiated by single photon radiopharmaceutical 99Tcm-methylenediphosphonate (99Tcm-MDP), 99Tcm-macroaggregated albumin (99Tcm-MAA), 99Tcm-diethylentriaminpentaacetic acid (99Tcm-DTPA), 99Tcm-methoxyisobutyl isonitrile (99Tcm-MIBI) and 99Tcm-pyrophosphate (99Tcm-PYP) were (4.63±0.01), (1.71±0.01), (1.18±0.01), (7.19±0.03) and (4.18±0.01) mSv, respectively. Conclusions Radiopharmaceutical irradiation caused effective dose to the patients undergoing nuclear medicine examinations is from 1.08 to 7.19 mSv, while CT scan cause average effective dose is 8.80 mSv in PET-CT examination. |
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