| Lu Feng,Song Gang,Bi Mingwei,et al.Comparison of radiation field irradiated by different focusing modes of γ-knife[J].Chinese Journal of Radiological Medicine and Protection,2015,35(5):384-388 |
| Comparison of radiation field irradiated by different focusing modes of γ-knife |
| Received:October 13, 2014 |
| DOI：10.3760/cma.j.issn.0254-5098.2015.05.018 |
| KeyWords:γ-knife Radiation field Focusing mode Dose |
| FundProject:山东省科技发展计划(2009GG10002051) |
| Author Name | Affiliation | E-mail | | Lu Feng | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | | | Song Gang | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | | | Bi Mingwei | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | | | Xu Jiaang | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | | | Liu Qian | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | | | Chen Yingmin | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | | | Deng Daping | Institute of Radiation Medicine, Shandong Academy of Medicine Sciences, Jinan 250062, China | yanzhid@126.com |
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| Abstract:: |
| Objective To compare the single-shot fields irradiated by three focusing modes of γ-knife and explore the approaches for improving the quality of stereotactic radiosurgery. Methods GAFCHROMIC® EBT3 mode flushing-free film was used to measure the single-shot fields irradiated by multi-source static focusing modes, multi-source single-axis rotating focusing mode and single-source double-axis rotating focusing mode of γ-knife. Also the uniformity and penumbra of the single-shot fields were compared. Results The 2D dose distribution of the single-shot fields irradiated by three focusing modes of γ-knife was different. In the axis (x, y, z), the rang of penumbra axial length ratios of multi-source static focusing modes, multi-source single-axis rotating focusing mode and single-source double-axis rotating focusing mode were 0.13-0.48, 0.17-0.33 and 0.28-0.54, in the diagonal direction of the wings plane (NSD, PSD), were 0.31-0.39,0.38-0.43 and 0.54-0.72, respectively; the penumbra axial length ratio of single-source double-axis rotating focusing mode was bigger than in multi-source static focusing modes and multi-source single-axis rotating focusing mode. On the no-wings plane, the area ratios of 80% dose curve enveloped and 50% dose curve enveloped(A80%/A50%)were 0.40,0.47 and 0.19, on the wings plane, were 0.61,0.53 and 0.35, respectively. The field uniformity of multi-source static focusing modes and multi-source single-axis rotating focusing mode were superior to single-source double-axis rotating focusing mode. Conclusions Considering dose distribution of the single-shot fields, the multi-source static focusing modes devices and the multi-source single-axis rotating focusing mode devices should be preferred, when important tissues and organs are adjacent to the target areas. Compared with single-source double-axis rotating focusing mode, both multi-source static focusing modes and multi-source single-axis rotating focusing mode could make more target areas to be surrounded by high dose region. |
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