| Sun Zhijuan,Wang Jixian,Xiang Jian,et al.Estimation of radiogenic cancer risk coefficients of stomach cancer in Chinese population[J].Chinese Journal of Radiological Medicine and Protection,2015,35(4):282-286 |
| Estimation of radiogenic cancer risk coefficients of stomach cancer in Chinese population |
| Received:July 15, 2014 |
| DOI：10.3760/cma.j.issn.0254-5098.2015.04.011 |
| KeyWords:Excess risk of radiation carcinogen Risk transportation between populations Baseline of cancer incidence rate Stomach cancer |
| FundProject:卫生部卫生标准制(修)订项目(20130702);教育部高等学校博士学科点专项科研基金资助项目-新教师类(20121106120041) |
| Author Name | Affiliation | | Sun Zhijuan | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | Wang Jixian | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | Xiang Jian | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | Zhao Yongcheng | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | Chen Jingyun | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | Yang Qingqing | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China | | Fan Saijun | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin 300192, China |
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| Abstract:: |
| Objective To estimate the excess relative risk coefficients of stomach cancer for Chinese population attributable to ionizing radiation. Methods The excess relative risk and excess absolute risk coefficients of stomach cancer were estimated based on Life Span Study by using risk models developed by BEIR Ⅶ committee (Biological Effect of Ionizing Radiation). Guided by transportation methods from Life Span Study to Americans, we determined that transportation method for Chinese population includes both multiplicative and additive models with a weight of 0.7 and 0.3 respectively, on an arithmetic scale. Besides, curve fitting was used to obtain sex- age- specific stomach cancer baseline incidence based on Chinese cancer annual report. Then, Chinese excess relative risk coefficients of stomach cancer were obtained by substituting excess relative risk, excess absolute risk of Life Span Study and Chinese baseline incidence rate into risk transportation model. Results Excess relative risk coefficients of stomach cancer for Chinese population are 0.26/Sv for male and 0.64/Sv for female, whose exposure age is 30 years old and cancer age is 60 years old. Coefficients increase with decreased exposure age and cancer age. Conclusions Excess relative risk coefficients of stomach cancer for Chinese population are by larger higher than that of Life Span Study, and their sex-age tendency are similar. |
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