| Zhou Chong,Ren Hongrong,Bu Xiangzhao,et al.Dosimetric comparison of volumetric modulation arc radiotherapy with flattening filter-free beams with IMRT for upper thoracic esophageal cancer[J].Chinese Journal of Radiological Medicine and Protection,2015,35(4):261-264 |
| Dosimetric comparison of volumetric modulation arc radiotherapy with flattening filter-free beams with IMRT for upper thoracic esophageal cancer |
| Received:October 07, 2014 |
| DOI：10.3760/cma.j.issn.0254-5098.2015.04.006 |
| KeyWords:Volumetric modulated arc therapy Intensity-modulated radiotherapy Esophageal cancer Dosimetry |
| FundProject:徐州市青年后备人才项目(2014005) |
| Author Name | Affiliation | E-mail | | Zhou Chong | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Ren Hongrong | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Bu Xiangzhao | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Ding Ji | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Ruan Xiaobo | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Zhang Wei | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Li Xiangyang | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Guo Lin | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Liu Ling | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | | | Yin Haitao | Department of Radiation Oncology, The Central Hospital of Xuzhou, The Cancer Institute of Southeast University, Xuzhou 221006, China | baixia1108@126.com |
|
| Hits: 3829 |
| Download times: 3250 |
| Abstract:: |
| Objective To compare the dosimetric difference between RapidArc with flattening filter-free Beams (RA-FFF) and static gantry intensity-modulated radiotherapy (IMRT) for upper thoracic esophageal cancer by means of Varian TrueBeamTM accelerator. Methods A total of 10 patients with upper thoracic esophageal cancer staged cT2-3N0-1M0 were enrolled. RA-FFF and IMRT treatment plans with radical intent were generated by Varian EclipseTM TPS 10.0.4 for each patient. All plans were prescribed 60 Gy in 30 fractions. The RA-FFF plans were compared with IMRT in terms of dosimetric quality and delivery efficiency. Results Both of the two plans provided similar conformity index, while IMRT had a improved homogeneity index than that of RA-FFF(t=7.298, P=0.008). For the lung, the values of V20, V5 in RA-FFF plan was lower than that of IMRT plan(t=2.451, 2.604 P<0.05). The treatment planning time of RA-FFF plans were longer than that of IMRT plans[(5.3±1.4), (3.5±1.7) h, t=2.585,P<0.05]. The monitor units for RA-FFF and IMRT were 632±213 and 734±132(t=-1.287,P=0.084), respectively. The treatment time of RA-FFF and IMRT were 2.2±0.9 and 4.5±1.3, respectively(t=4.60, P<0.01). Conclusions For patients with upper thoracic esophageal cancer, RA-FFF plan, compared with IMRT plan, has a similar target coverage and better dose sparing to the lungs. In addition, RA-FFF plan has fewer MUs, less treatment time and better treatment efficiency. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
