| Chen Jingyun,Sun Zhijuan,Ren Guanhua,et al.Transfer of radiation related leukemia risk from Japanese population to Chinese population[J].Chinese Journal of Radiological Medicine and Protection,2015,35(2):134-138 |
| Transfer of radiation related leukemia risk from Japanese population to Chinese population |
| Received:July 25, 2014 |
| DOI：10.3760/cma.j.issn.0254-5098.2015.02.014 |
| KeyWords:Excess relative risk(ERR) Radiogenic cancer Risk transfer between populations Leukemia Weighting factors |
| FundProject: |
| Author Name | Affiliation | E-mail | | Chen Jingyun | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | | | Sun Zhijuan | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | | | Ren Guanhua | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | | | Yang Qingqing | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | | | Wang Jixian | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | | | Fan Saijun | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | | | Zhao Yongcheng | Tianjin Key Laboratory of Radiation Medicine and Molecular Nuclear Medicine, Institute of Radiation Medicine, Chinese Academy of Medical Science & Peking Union Medical College, Tianjin 300192, China | zhaoyc60@irm-cams.ac.cn |
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| Abstract:: |
| Objective To estimate the averaged excess relative risk(ERR) in Chinese population based on the radiogenic cancer risk of leukemia in Japanese atomic bomb survivor cohort, and to discuss proper method suitable for risk transfer between populations.Methods Based on BEIRⅦ radiogenic cancer model and population transfer model, and the 2009 Chinese leukemia baseline rates given in 2012 Chinese Cancer Registry Annual Report, comparison was made of population incidences in seveal countries to adjust the weighting factors.Results The ERR of three subtypes of leukemia as a whole was obtained, and the weighting factors for risk transfer model was assumed. The additive factor for male was 0.2, and the multiplicative factor was 0.8, while the additive factor for female was 0.15, and the multiplicative factor was 0.85.Conclusions For the risk transfer between populations, weighting factor was adjusted as a whole to obtain the ERR value for estimating the risk to Chinese population. The risk transfer method suitable for Chinese population was obtained by using the incidence rate available for Chinese population to directly transfer radiation-induced leukemia risk to Chinese from Japanese. |
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