Hou Dongliang,Fang Tong,Liu Bo,Song Linan,Sun Baojin,Chen Li.Comparative evaluation of CT and CT/MR DWI images for GTV delineation in precision radiotherapy for esophageal squamous cell carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2014,34(12):916-918
Comparative evaluation of CT and CT/MR DWI images for GTV delineation in precision radiotherapy for esophageal squamous cell carcinoma
Received:June 19, 2014  
DOI:10.3760/cma.j.issn.0254-5098.2014.12.009
KeyWords:Target delineation  Esophageal neoplasm  Diffusion-weighted magnetic resonance imaging  Image fusion
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Author NameAffiliationE-mail
Hou Dongliang Department of radiotherapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China  
Fang Tong Department of radiotherapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China fangt369@163.com 
Liu Bo Department of radiotherapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China  
Song Linan Department of radiotherapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China  
Sun Baojin Department of radiotherapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China  
Chen Li Department of radiotherapy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China  
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Abstract::
      Objective To evaluate the difference between CT and CT/MR DWI images for gross tumor volume (GTV) delineation in precision radiotherapy for esophageal squamous cell carcinoma. Methods 20 patients with pathologically confirmed as esophageal squamous cell carcinoma were selected for target delineation. The GTV based on CT and CT/MR DWI images of the patients were delineated by six radiation oncologists. The mean, standard deviation, coefficient of variation (CV=standard deviation/mean) of GTV volume, the ratio of minimum value and maximum value (ratio=maximum value/minimum value) of the GTV volume were calculated. And the CV and ratio of the GTV by the two methods were compared. Results The biggest difference of GTV volume on CT and on CT/MR DWI images was 55.71 and 13.89 cm3 (F=12.80,P<0.05). The CV on CT and CT/MR DWI images were 0.30±0.08, 0.11±0.04 (Z=-3.92, P<0.05), and the ratio of GTV volume were 2.38±0.62, 1.34±0.13, respectively (Z=-3.92, P<0.05). Conclusions CT/MR DWI images could display GTV more directly, which may help to increase consistency of GTV for esophageal squamous cell carcinoma delineation among different radiation oncologists.
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