| Jiang Huayong,Zhang Yongqian,Wang Yadi,Xu Weidong,Gao Junmao,Zhang Fuli,Yao Bo.Position modification and actual radiation dose in parotids for head and neck cancers treated with TomoTherapy[J].Chinese Journal of Radiological Medicine and Protection,2014,34(11):845-849 |
| Position modification and actual radiation dose in parotids for head and neck cancers treated with TomoTherapy |
| Received:December 21, 2013 |
| DOI：10.3760/cma.j.issn.0254-5098.2014.11.011 |
| KeyWords:Head and neck cancer TomoTherapy Parotid Actual radiation dose Deformation image registration |
| FundProject: |
| Author Name | Affiliation | E-mail | | Jiang Huayong | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | | | Zhang Yongqian | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | | | Wang Yadi | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | wangyadi@hotmail.com | | Xu Weidong | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | | | Gao Junmao | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | | | Zhang Fuli | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | | | Yao Bo | Department of Radiation Oncology, General Hospital of Beijing Military Command, Beijing 100700, China | |
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| Abstract:: |
| Objective To analyze the impact of parotid's position and volume changing on radiation dose for head and neck cancer treated with TomoTherapy. Methods Totally 12 patients with head and neck cancer were treated with TomoTherapy. Before the treatment, the dose distribution was recalculated with MVCT images, which would obtain the parameters of position, volume and actual radiation dose for parotids. Results The volume of parotids in Plan2 was significantly lower than in Plan1, and the percentage reduction was 29.06% and 31.78% for left and right parotid, respectively (Z=6.77, 3.06,P<0.05).Distance between the COM(center of mass) of parotids and the midline of body was significantly smaller in Plan2 than in Plan1, and the percentage reduction was 6.72% and 6.19% (t=5.14, 5.80,P<0.05) at left and right side, respectively. Average dose andV26 for both parotids were higher than those in Plan1, increasing by an average of 37.74%, 25.08%(Z=-6.03, -5.31,P<0.05) for left parotid and 30.45%, 19.33% (Z=-5.43,-3.26,P<0.05) for right parotid, respectively. Conclusions The actual radiation dose to parotids was significantly increased during the radiation therapy for patients with head and neck cancer. There was a linear correlation between the decrease of distance between the COM of parotids and the midline of body and the percentage increase of parotids' radiation dose. No correlation between the reduction of parotids' volume and dose to parotids. In order to reduce the parotids' radiation dose, modification of treatment plan at the appropriate time is essential. |
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