| .Comparison of internal gross target volumes delineated on the maximum intensity projection of four-dimensional CT images and positron emission tomography-CT for primary thoracic esophageal cancer[J].Chinese Journal of Radiological Medicine and Protection,2014,34(9):683-687 |
| Comparison of internal gross target volumes delineated on the maximum intensity projection of four-dimensional CT images and positron emission tomography-CT for primary thoracic esophageal cancer |
| Received:December 20, 2013 |
| DOI：10.3760/cma.j.issn.0254-5098.2014.09.010 |
| KeyWords:Thoracic esophageal cancer 18F-FDG PET-CT Four-dimensional computed tomography Standardized uptake value Internal gross target volume |
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| Abstract:: |
| Objective To compare volumetric size, conformity index (CI), degree of inclusion (DI) of internal gross target volumes (IGTV) delineated on 4D-CT-MIP and PET-CT images for primary thoracic esophageal cancer. Methods Fifteen patients with thoracic esophageal cancer sequentially underwent enhanced 3D-CT, 4D-CT and PET-CT simulation scans. IGTVMIP was obtained by contouring on 4D-CT maximum intensity projection (MIP). The PET contours were determined with nine different threshold methods (SUV≥ 2.0, 2.5, 3.0, 3.5), the percentages of the SUVmax (≥20%, 25%, 30%, 35%, 40%) and manual contours. The differences in size, conformity index (CI), degree of inclusion (DI) of different volumes were compared.Results The volume ratios (VRs) of IGTVPET2.5 to IGTVMIP, IGTVPET20% to IGTVMIP, IGTVPETMAN to IGTVMIP were 0 .86, 0.88, 1.06, respectively, which approached closest to 1. The CIs of IGTVPET2.0,IGTVPET2.5,IGTVPET20%,IGTVPETMAN and IGTVMIP which were 0.55, 0.56, 0.56, 0.54,0.55, respectively, were significantly larger than other CIs of IGTVPET and IGTVMIP(Z=-3.408-2.215,P<0.05). There were no statistical significance in the DIs of IGTVMIP and IGTVPET2.5,IGTVMIP and IGTVPET20%, IGTVMIP and IGTVPETMAN (0.77,0.82,0.71,0.67, 0.68,0.82,P>0.05). Conclusions The targets delineated based on SUV threshold setting of ≥2.5, 20% of the SUVmax and manual contours on PET images correspond better with the target delineated on maximum intensity projection of 4D-CT images than other SUV thresholding methods. |
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