Xing Xiaofen,Chu Xuegang,Cui Tong,Zheng Xuliang,Guo Ruisong.A clinical test and application research of IMRT 3D dose verification system[J].Chinese Journal of Radiological Medicine and Protection,2014,34(6):427-430 |
A clinical test and application research of IMRT 3D dose verification system |
Received:July 11, 2013 |
DOI:10.3760/cma.j.issn.0254-5098.2014.06.007 |
KeyWords:Intensity-modulated radiotherapy Quality assure Three-dimensional dose verification Dosimetry |
FundProject: |
Author Name | Affiliation | E-mail | Xing Xiaofen | Department of Radiation Oncology, Shanxi Tumor Hospital, Taiyuan 030013, China | | Chu Xuegang | Department of Radiation Oncology, Shanxi Tumor Hospital, Taiyuan 030013, China | | Cui Tong | Department of Radiation Oncology, Shanxi Tumor Hospital, Taiyuan 030013, China | | Zheng Xuliang | Department of Radiation Oncology, Shanxi Tumor Hospital, Taiyuan 030013, China | | Guo Ruisong | Department of Radiation Oncology, Shanxi Tumor Hospital, Taiyuan 030013, China | sxgrs@163.com |
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Abstract:: |
Objective To test the accuracy of a three-dimensional dose verification system CompassR, which reconstructing dose distribution based on measurements and independent dose calculation, and to evaluate the feasibility of its application in clinical intensity-modulated radiotherapy(IMRT) quality assure. Methods A set of square-wave chart patterns of 2 cm, 1 cm and 0.5 cm gaps was designed and 11 completed IMRT lung plans were selected for the test. EDR2 film and the ionization chamber were used for test and verifying of plane dose distribution and some special points dose of CompassR. The IMRT phantom plans were verified by CompassR with three-dimension based on anatomical information. Parameters including the volume γ pass rate and the average dose deviation were tested using dose volume histograms. Results In square-wave chart patterns test, the dose distribution reconstructed and calculated by CompassR coincided with the measurement using film. The γ pass rates (3%/3 mm,2%/2 mm) exceeded 90%. When the width of field is 0.5 cm, the γ pass rate was a little lower on account of the penumbra zone. Compared to the dose distribution profile which was measured by film, the maximum deviations of the dose distribution profile which was reconstructed and calculated by CompassR were 3.21% and 2.70%. The absolute dose deviation of specific point in the IMRT plans was less than 3%,the maximum deviation occurred in the lung. Compared to film, the averageγpass rates on the isocenter plain in IMRT plan were (94.65+1.93)% (3%/3 mm) which was reconstructed by CompassR. In three-dimensional dose verification, the volume γ pass rates of targets and risk organs were not less than 90%, and the deviation of average dose was less than 1%. Conclusions Accuracy of the tested system satisfies the demand of IMRT dose verification. CompassR could provide information of volumetric dosimetry and anatomical location of dose error, which is benefit for evaluating the clinical value of verification result. |
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