Jiang Jun,Huang Meiping,Liang Changhong,Zhuang Jian,Yang Lin,Li Jinglei,Liu Qishun,Liu Hui,Cao Ximing.Application of iDose in low-dose CT cardiac imaging in patients with congenital heart disease[J].Chinese Journal of Radiological Medicine and Protection,2014,34(4):306-309
Application of iDose in low-dose CT cardiac imaging in patients with congenital heart disease
Received:June 22, 2013  
DOI:10.3760/cma.j.issn.0254-5098.2014.04.018
KeyWords:Congenital heart disease  Tomography, X-ray computed  Iterative reconstruction  Low-dose
FundProject:国家“十二五”科技支撑计划项目(2011BAI11B22);广东省科技支撑计划项目(2009B030801257,2006B36030026)
Author NameAffiliationE-mail
Jiang Jun 510080 广州, 广东省人民医院放射科  
Huang Meiping 广东省人民医院介入导管室 huangmeiping@126.com 
Liang Changhong 510080 广州, 广东省人民医院放射科  
Zhuang Jian 广东省人民医院心外科  
Yang Lin 510080 广州, 广东省人民医院放射科  
Li Jinglei 510080 广州, 广东省人民医院放射科  
Liu Qishun 510080 广州, 广东省人民医院放射科  
Liu Hui 510080 广州, 广东省人民医院放射科  
Cao Ximing 510080 广州, 广东省人民医院放射科  
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Abstract::
      Objective To evaluate the value of iterative reconstruction (iDose) in low-dose CT cardiac imaging in patients with congenital heart disease (CHD). Methods Eighty-eight consecutive CHD patients referred for preoperative or post-operative CT were randomly diveded into 4 groups and undergone a prospective ECG-gated MDCT angiography with protocol A (routine low-dose depending on patient weight), B (30% of A), C (50%), and D (70%D), respectively. Filtered back projection (FBP) and grades 2,4, 6 of iDose were used for all reconstruction. Noises were measured at the root of ascending aorta and main pulmonary artery. Image qualities were graded (scale from one to five) and compared among 4 groups. Results The lowest image noise was measured in images reconstructed with grade 6 of iDose(P<0.05) while the highest one was measured in that with FBP in all groups. The subjective scores in Group D with iDose 6 reconstruction were no less than 3. The subjective score in Group D with iDose 6 was similar to that in Group A with FBP. Effective radiation dose in group D was (0.65±0.43)mSv. Conclusion Using iDose technique would reduce noise and improve image quality effectively. Grade 6 of iDose might be the best choice and would reduce effective dose by 70% in MDCT angiography in CHD patients.
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