| Ni Qianxi,Tang Dihong,Zhang Jiutang.Preliminary clinical research on the afterloading brachytherapy inverse intensity-modulated radiotherapy of gynecological tumor[J].Chinese Journal of Radiological Medicine and Protection,2014,34(4):286-288 |
| Preliminary clinical research on the afterloading brachytherapy inverse intensity-modulated radiotherapy of gynecological tumor |
| Received:June 19, 2013 |
| DOI：10.3760/cma.j.issn.0254-5098.2014.04.012 |
| KeyWords:Gynecologic tumor Inverse planning simulated annealing(IPSA) Dosimetry Organs at risk Radioactive complications |
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| Abstract:: |
| Objective To evaluate the clinical value of the afterloading brachytherapy inverse intensity-modulated radiotherapy of gynecological tumor. Methods Twenty patients with cervical cancer, were randomly divided into A and B groups, 10 cases for each group. Group A received the afterloading brachytherapy inverse intensity-modulated radiotherapy. Group B received the three-dimensional comformal afterloading brachytherapy. The target volume dose distribution, organs at risk (rectum, bladder), short-term curative effect and radioactive complications were analyzed on both groups. Results The dose homogeneity index of the target volume of group A was 52.43±0.45, better than that of group B(46.37±1.45)(t=0.92,P<0.05).The maximum dose of rectum and bladder of group A were about 37%, 35%, less than that of group B(t=1.34,1.39,P<0.05). The 75% prescription dose irradiated volume of rectum and bladder of group A were about only 1/2 of group B(t=1.23,1.13,P<0.05).The local control rate of 96% for group A was better than 93% for group B(t=1.25,P<0.05). Conclusions Afterloading brachytherapy inverse intensity-modulated radiotherapy technique could be better than the three-dimensional comformal afterloading brachytherapy. It should be recommended for gynecological tumor. |
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