Zhang Hongtao,Tang Fulong,Wu Lili,Gao Zhen,Sun Meiling,Zhao Jing,Wang Zeyang,Wang Juan*.Effect of TPS calculating grid on dose calculation accuracy for 125I seed implantation[J].Chinese Journal of Radiological Medicine and Protection,2014,34(1):59-61
Effect of TPS calculating grid on dose calculation accuracy for 125I seed implantation
Received:June 05, 2013  
DOI:10.3760/cma.j.issn.0254-5098.2014.01.016
KeyWords:125I seed  Brachytherapy  Dose
FundProject:河北省科学技术厅支撑项目(11276103D-34)
Author NameAffiliationE-mail
Zhang Hongtao Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Tang Fulong Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Wu Lili Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Gao Zhen Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Sun Meiling Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Zhao Jing Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Wang Zeyang Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China  
Wang Juan* Department of Oncology, Hebei General Hospital, Shijiazhuang 050051, China lizizhiru@163.com 
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Abstract::
      Objective To study the influence of TPS calculation grid on the dose calculation accuracy for 125I seed implantation. Methods Ten verification plans were selected randomly. Calculating grids were modulated into four groups: 128×128, 96×96, 64×64 and 32×32. Under the conditions of same seeds number, location, activity and target volume, the doses resulting from every plan were calculated using TPS to obtain D90,V90, V100 and V150. Data were grouped into A, B, C and D by means of the calculating grid of 128×128, 96×96, 64×64 and 32×32. The percentage errors of four groups were calculated. Results The arithmetic mean D90 of group A, B, C and D were(7 178.8±2 237.7), (7 072.7±2 240.8), (6 889.1±2 305.5) and (6 351.0±2 515.7)cGy, respectively. The arithmetic mean of percentage errors of the four groups were(0.74±0.6)%, (-0.89±2.2)%, (-3.85±4.7)% and (-10.46±4.8)% (F=8.95, P<0.05). The V90 of group A, B, C and D were (93.12±0.32)%, (92.75±0.29)%, (91.87±1.28)% and (88.06±5.06)%(F=7.85, P<0.05). The V100 of group A, B, C and D were (90.21±0.14)%, (89.67±0.64)%, (88.68±1.80)% and (84.10±6.56)%(F=6.64, P<0.05). The V150 of group A, B, C and D were (73.48±3.49)%, (72.66±3.96)%, (71.33±4.83)% and (65.41±9.49)% (F=3.90,P<0.05). Conclusions The dose calculating accuracy of 125I seeds implantation is influenced significantly by TPS calculating grid. The calculating grid of 128×128 should be used as long as the calculating speed is not reduced.
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