JIANG Jing,KONG Ting,HUANG Bo,et al.Effect of low-dose radiation on ocular lens of radiation workers:Meta-analysis[J].Chinese Journal of Radiological Medicine and Protection,2013,33(6):640-644 |
Effect of low-dose radiation on ocular lens of radiation workers:Meta-analysis |
Received:April 10, 2013 |
DOI:10.3760/cma.j.issn.0254-5098.2013.06.019 |
KeyWords:Radiation workers Ionizing radiation Lens opacity Meta-analysis |
FundProject:国家863项目(2012AA063501);国家自然科学基金(81272994) |
Author Name | Affiliation | E-mail | JIANG Jing | Academy of Environmental Medicine and Radiation Health, University of South China, Hengyang 421001, China | | KONG Ting | Academy of Environmental Medicine and Radiation Health, University of South China, Hengyang 421001, China | | HUANG Bo | Academy of Environmental Medicine and Radiation Health, University of South China, Hengyang 421001, China | | ZHOU Ping-kun | 北京放射医学研究所 | | RANG Wei-qing | Academy of Environmental Medicine and Radiation Health, University of South China, Hengyang 421001, China | nhurwq@126.com |
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Abstract:: |
Objective To comprehensively analyze the effect of low-dose radiation on the lens of the eye of radiation workers. Methods The papers dealing with the relationship between occupational radiation exposure and the lens of the eye were collected by retrieving documents of the domestic and foreign medical information databases with references to other papers. There were 28 papers finalized with 17 608 workers included in the Meta-analysis. Stata12.0 was used for Meta-analysis, Q-test and I2 statistic for heterogeneity test, and funnel regression method, Begg's rank method and Egger's regression method for publication bias. Results The pooling odds ratio (OR) opacity in radiation workers were 2.51(2.01,3.13), 4.03(2.77,5.85), respectively. Conclusions Low-dose radiation may lead to negative impact on ocular lens under the current occupational protection conditions. The proportion of posterior subcapsular opacity in radiation-related cataract is higher than that in age-related cataract. It is important to strengthen radiation protection of ocular lens. |
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