LI Ding-jie,WU Hui,MAO Rong-hu,et al.Application of CT image-guided technology in radiotherapy of the mid-and upper-thoracic esophageal carcinoma[J].Chinese Journal of Radiological Medicine and Protection,2013,33(6):623-625
Application of CT image-guided technology in radiotherapy of the mid-and upper-thoracic esophageal carcinoma
Received:February 26, 2013  
DOI:10.3760/cma.j.issn.0254-5098.2013.06.014
KeyWords:Esophageal carcinoma radiotherapy  CT-based image guidance  Set-up error  Organ motion  Clinical target volume margins
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Author NameAffiliationE-mail
LI Ding-jie Henan Province Tumor Hospital, Zhengzhou 450008, China  
WU Hui Henan Province Tumor Hospital, Zhengzhou 450008, China  
MAO Rong-hu Henan Province Tumor Hospital, Zhengzhou 450008, China  
YANG Cheng-liang Henan Province Tumor Hospital, Zhengzhou 450008, China  
LEI Hong-chang Henan Province Tumor Hospital, Zhengzhou 450008, China  
WANG Jian-hua Henan Province Tumor Hospital, Zhengzhou 450008, China huajianye@sina.cn 
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Abstract::
      Objective To compare the clinical target volume (CTV) expanding margins in the mid-and upper-thoracic esophageal carcinoma during radiotherapy measured with and without online image guidance technique by CT on rail. Methods100 patients with mid-and upper-thoracic esophageal carcinoma undergoing intensity modulated radiotherapy received CT scanning.Image registration was conducted between the scanning results and the planned CT images, thus set-up error data were acquired and got on-line correction. Fifty patients were randomly selected to undergo additional post-treatment CT scanningso as to analyze the revised residuals, displacement during treatment, and infra-fraction GTV shifts. Results Compared to the radiotherapy without CT-based image guidance, the CTV expanding margins obtained with CT-based image guidance was reduced significantly from 9.1, 8.8 and 6.1 mm to 4.1, 4.5 and 4.3 mm in the left-right, head-feet, and belly-back directions respectively. Conclusions The on-line image-guided technology significantly improves the accuracy of target and reduces the CTV expanding margins.
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