| SUN Jian-guo,CHEN Zheng-tang,ZHOU Yi-bing,LI De-zhi,LI Guang-hui,LI Qi-ming,PU Ping,ZHANG Yu-ping,WAN Jiu-qing,YANG Ding-qiang.The clinical test of domestic linear accelerator AccStar[J].Chinese Journal of Radiological Medicine and Protection,2013,33(4):409-412 |
| The clinical test of domestic linear accelerator AccStar |
| Received:November 05, 2012 |
| DOI：10.3760/cma.j.issn.0254-5098.2013.04.020 |
| KeyWords:Demestic accelerator Radiation therapy Nasopharyngeal carcinoma Lung cancer |
| FundProject:国家自然科学基金(81272496) |
| Author Name | Affiliation | | SUN Jian-guo | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | CHEN Zheng-tang | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | ZHOU Yi-bing | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | LI De-zhi | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | LI Guang-hui | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | LI Qi-ming | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | PU Ping | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | ZHANG Yu-ping | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | WAN Jiu-qing | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China | | YANG Ding-qiang | Institute of Cancer, Xinqiao Hospital, Third Military Medical University, Chongqing 400037, China |
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| Abstract:: |
| Objective To clinically validate the technical parameters of domestic linear accelerator AccStar, and to assess its accuracy, efficiency and safety in clinical application based on the relevant national standards. Methods Volunteers who suffered nasopharyngeal carcinoma and lung cancer were selected to accept conformal radiation therapy using AccStar medical linear accelerator. A variety of tests were conducted based on the national standards for clinical trials. The clinical efficacy of the radiation therapy was assessed based on the RECIST standard. Acute radiation response was evaluated based on the RTOG standards, and the mechanical and the geometric properties of the accelerator were tested and corrected based on the international standards of IEC and the national standards. Results Forty-three cases were included, of which there were 21 patients with nasopharyngeal carcinoma, and 22 with non small cell lung cancer. All of them received the clinical treatment and auxiliary examination. The overall disease control rate reached 100% and the patients could tolerate the radiation reactions, most of which were skin and oral mucosa reactions. During the clinical trials, all the technical parameters were tested, including the physical parameters and performance parameters, could meet the standards mentioned above. Conclusions The accuracy, efficiency and safety of AccStar meet the relevant national standards and the clinical requirements, so that it can be applied to clinical setting. |
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