| WU Meng-lin,ZHANG Xue-ning,GUO Qi,ZHENG Jing-jing,ZHANG Yi-pei,XU De-sheng,WEI Lu,SHI Dai.Effect of gamma knife surgery for primary orbital optic nerve sheath meningioma upon visual control and influencing factors thereof[J].Chinese Journal of Radiological Medicine and Protection,2013,33(4):396-399 |
| Effect of gamma knife surgery for primary orbital optic nerve sheath meningioma upon visual control and influencing factors thereof |
| Received:November 22, 2012 |
| DOI：10.3760/cma.j.issn.0254-5098.2013.04.015 |
| KeyWords:Primary optic nerve sheath meningioma Gamma knife surgery Radiotherapy Visual acuity Influencing factors |
| FundProject: |
| Author Name | Affiliation | E-mail | | WU Meng-lin | Department of Radiology, Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China | | | ZHANG Xue-ning | Department of Radiology, Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China | luckyxn@yahoo.com.cn | | GUO Qi | Department of Radiology, Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China | | | ZHENG Jing-jing | Department of Radiology, Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China | | | ZHANG Yi-pei | 神经外科暨伽玛刀中心 | | | XU De-sheng | 神经外科暨伽玛刀中心 | | | WEI Lu | Department of Radiology, Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China | | | SHI Dai | Department of Radiology, Second Affiliated Hospital of Tianjin Medical University, Tianjin 300211, China | |
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| Abstract:: |
| Objective To investigate the effect of gamma knife surgery (GKS) in treatment of primary orbital optic nerve sheath meningioma (PONSM) upon visual control and to explore the factors influencing the visual acuity changes after GKS. Methods Totally 26 PONSM patients, 3 males and 23 females, aged 35.5 (4-66) years old, 2 pathologically confirmed and 24 confirmed by MRI, underwent GKS, and were followed up for 20.2 months (6-62 months). The efficacy of GKS was evaluated by the change of tumor volume and visual acuity. The relations between the change of visual acuity and different clinical features were analyzed. Results The vision control rate was 65.4%, and the tumor control rate was 96.2%. The onset age, onset speed, and preoperative shape of PONSM were significantly correlated with the visual change after GKS (P=0.034, 0.014, and 0.034 respectively). Conclusions The efficacy of GKS in patients with PONSM is fine, which depends on the onset age, onset speed,as well as the degree of radiation-induced side effect after GKS. |
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