DONG Fei,WANG Jing,WANG Ji-jun,et al.The analysis of total body irradiation in the hematopoietic reconstitution and short-term side-effects of autologous stem cell transplantation[J].Chinese Journal of Radiological Medicine and Protection,2013,33(3):232-234
The analysis of total body irradiation in the hematopoietic reconstitution and short-term side-effects of autologous stem cell transplantation
Received:January 31, 2013  
DOI:10.3760/cma.j.issn.0254-5098.2013.03.003
KeyWords:Total body irradiation  Autologous peripheral blood stem cell transplantation  Hematopoietic reconstitution  Side-effects
FundProject:卫生行业科研专项(201002009)
Author NameAffiliationE-mail
DONG Fei Department of Hematology, Peking University Third Hospital, Beijing 100191, China  
WANG Jing Department of Hematology, Peking University Third Hospital, Beijing 100191, China  
WANG Ji-jun Department of Hematology, Peking University Third Hospital, Beijing 100191, China  
HU Kai Department of Hematology, Peking University Third Hospital, Beijing 100191, China  
TIAN Lei Department of Hematology, Peking University Third Hospital, Beijing 100191, China  
WAN Wei Department of Hematology, Peking University Third Hospital, Beijing 100191, China  
FENG Kai-chao 山西省肿瘤医院血液科  
SU Li-ping 山西省肿瘤医院血液科  
SU Xu 中国疾病预防控制中心辐射防护与核安全医学所  
KE Xiao-yan Department of Hematology, Peking University Third Hospital, Beijing 100191, China crystal_bmu@163.com 
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Abstract::
      Objective To explore the influence of TBI in the conditioning regimen for autologous stem cell transplantation, as well as short-term side-effects. Methods To tally 103 patients were divided into TBI group and no TBI group with autologous stem cell transplantation during 1990-2012. The time required for hematopoietic reconstitution and the short-term side effects were analyzed. Results Between the two groups, the hematopoietic reconstitution time had no significant difference, but there was a high incidence of oral mucositis and gastrointestinal reaction in the TBI group (χ2=6.458,22.400,P<0.05), and the incidence of infection is not significant. Conclusions Given the preventive treatment, the TBI group has no more serious short-term side effects and better tolerance.
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