| DONG Fei,WANG Jing,WANG Ji-jun,et al.The analysis of total body irradiation in the hematopoietic reconstitution and short-term side-effects of autologous stem cell transplantation[J].Chinese Journal of Radiological Medicine and Protection,2013,33(3):232-234 |
| The analysis of total body irradiation in the hematopoietic reconstitution and short-term side-effects of autologous stem cell transplantation |
| Received:January 31, 2013 |
| DOI：10.3760/cma.j.issn.0254-5098.2013.03.003 |
| KeyWords:Total body irradiation Autologous peripheral blood stem cell transplantation Hematopoietic reconstitution Side-effects |
| FundProject:卫生行业科研专项(201002009) |
| Author Name | Affiliation | E-mail | | DONG Fei | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | | | WANG Jing | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | | | WANG Ji-jun | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | | | HU Kai | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | | | TIAN Lei | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | | | WAN Wei | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | | | FENG Kai-chao | 山西省肿瘤医院血液科 | | | SU Li-ping | 山西省肿瘤医院血液科 | | | SU Xu | 中国疾病预防控制中心辐射防护与核安全医学所 | | | KE Xiao-yan | Department of Hematology, Peking University Third Hospital, Beijing 100191, China | crystal_bmu@163.com |
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| Abstract:: |
| Objective To explore the influence of TBI in the conditioning regimen for autologous stem cell transplantation, as well as short-term side-effects. Methods To tally 103 patients were divided into TBI group and no TBI group with autologous stem cell transplantation during 1990-2012. The time required for hematopoietic reconstitution and the short-term side effects were analyzed. Results Between the two groups, the hematopoietic reconstitution time had no significant difference, but there was a high incidence of oral mucositis and gastrointestinal reaction in the TBI group (χ2=6.458,22.400,P<0.05), and the incidence of infection is not significant. Conclusions Given the preventive treatment, the TBI group has no more serious short-term side effects and better tolerance. |
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