| LI Yong-wu,SUN Xiao-nan,WANG Qi,et al.A dosimetric comparison of the tangential beams IMRT with multifield beams IMRT of the chest wall in postmastectomy breast cancer recurrent patients[J].Chinese Journal of Radiological Medicine and Protection,2013,33(2):155-157 |
| A dosimetric comparison of the tangential beams IMRT with multifield beams IMRT of the chest wall in postmastectomy breast cancer recurrent patients |
| Received:August 13, 2012 |
| DOI：10.3760/cma.j.issn.0254-5098.2013.02.011 |
| KeyWords:Postmastectomy breast cancer Recurrence Chest wall Intensity modulated radiotherapy Treatment planning |
| FundProject: |
| Author Name | Affiliation | E-mail | | LI Yong-wu | Department of Radiation Oncology, Sir RunRun Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China | | | SUN Xiao-nan | Department of Radiation Oncology, Sir RunRun Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China | sunxiaonan@hotmail.com | | WANG Qi | Department of Radiation Oncology, Sir RunRun Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China | | | LIU Hai | Department of Radiation Oncology, Sir RunRun Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China | | | SHI Guo-zhi | Department of Radiation Oncology, Sir RunRun Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou 310016, China | |
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| Abstract:: |
| Objective To compare the dose distribution of reserved planned tangential beam IMRT(2-field IMRT) with multifields beams IMRT(6-field IMRT) of the bulk-recurrent chest wall in postmastectomy breast cancer patients. Methods For 8 patients with chest wall in postmastectomy breast cancer bulk-recurrence, 2-field IMRT and 6-field IMRT plans were generated on PTV in Pinnacle Planning System. The prescribed dose of PTV was 50 Gy in 25 fractions and GTV was 66-70 Gy which irradiated incrementally by subsequent plan in 8-10 fractions. The conformal index (CI) and homogeneity index (HI) of 95% of prescribed dose over PTV were compared, while the dose distribution on ipsilateral lung and heart were evaluated. Results The CI of PTV by 6-field IMRT (0.66±0.08) was higher than that of the 2-field IMRT (0.53±0.10)(t=7.99, P＜0.05). The HI of PTV by 6-field IMRT (1.36±0.08) was lower than that of 2-field IMRT (2.19±0.78)(t=9.04, P＜0.05).There was no statistical difference in V5, V10, V20 and V35 for ipsilateral lung and in Dmax, V35 and Dmean for heart between two plans. Conclusions Compared with 2-field IMRT, 6-field IMRT might have a better dose distribution on planning target volume(PTV) for chest wall in postmastectomy breast cancer bulk-recurrence patients, but there is no significant difference in dose-volume of ipsilateral lung and heart between two plans. |
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