| HAN Lin,ZHAO Feng-ling,WANG Xi-ai,et al.Analysis of chromosomal aberration in seven medical staffs suspected with exposure to ionizing radiation[J].Chinese Journal of Radiological Medicine and Protection,2012,32(6):607-609 |
| Analysis of chromosomal aberration in seven medical staffs suspected with exposure to ionizing radiation |
| Received:April 09, 2012 |
| DOI：10.3760/cma.j.issn.0254-5098.2012.06.011 |
| KeyWords:Ionizing radiation Medical staff Chromosomal aberration |
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| Abstract:: |
| Objective To investigate the chromosomal aberrations in seven medical staffs suspected with exposure to ionizing radiation and to speculate its possible causation. Methods The hospital staffs, including 6 females and 1 male, worked in a clinical laboratory where a CT room was located downstairs. The thickness of precast slab between these two rooms was 6 cm. Peripheral blood lymphocytes of seven staffs were examined for conventional chromosomal aberrations. Results The frequencies of dicentrics in the peripheral lymphocytes of 4 females were from 0.40% to 1.60% that was significantly higher than the spontaneous frequency of dicentrics (0.03%, χ2=36.79, P<0.05). The translocation was observed in the lymphocytes from all subjects with frequencies from 0.33% to 1.20%, obviously higher than its spontaneous frequency of 0.01% (χ2=42.90, P<0.05). Conclusion These staffs suffer from ionizing radiation. |
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