WU Qin-hong,LI Xue-nan,LIU Chun-ling,ZHU Bao-quan,TIAN Li-hong,ZHANG Qing-wen,ZHU Meng,QIU Xi,WANG Chan,LI Gao-feng.Evaluation of setup errors for head-and-neck cancer localized with final isocenter marking method via cone beam CT[J].Chinese Journal of Radiological Medicine and Protection,2012,32(3):301-303
Evaluation of setup errors for head-and-neck cancer localized with final isocenter marking method via cone beam CT
Received:November 09, 2011  
DOI:10.3760/cma.j.issn.0254-5098.2012.03.020
KeyWords:Cone beam CT  Final isocenter marking method  Setup error  CT simulation
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Author NameAffiliationE-mail
WU Qin-hong Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
LI Xue-nan Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
LIU Chun-ling Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
ZHU Bao-quan Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
TIAN Li-hong Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
ZHANG Qing-wen Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
ZHU Meng Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
QIU Xi Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
WANG Chan Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China  
LI Gao-feng Department of Radiation Oncology, Beijing Hospital, Ministry of Health, Beijing 100730, China lgf6243@163.com 
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Abstract::
      Objective To evaluate the setup errors of image guided radiation therapy (IGRT) for head-and-neck cancer using kilovoltage cone beam CT(kV CBCT).Methods 256 patients with head-and-neck cancer were treated with intensity modulated radiation therapy (IMRT) from March 2009 to October 2011. All patients were immobilized with head-and-neck mask and localized with final isocenter marking method using the Philips PQS CT or Philips Brilliance CT Big Bore scanners, which were equipped with LAP movable laser systems. The CT images were transferred to a Varian Eclipse V8.6 workstation for contouring and planning. A kV cone-beam CT scans was acquired, and registered before the treatment for every patient on a Varian iX linear accelerator via OBI system. The setup errors in the right-left (RL), superior-inferior (SI), and anterior-posterior (AP) directions were recorded.Results The setup errors for the 473 datasets followed a Gaussian distribution. The systematic errors ± random errors in the RL, SI and AP were(-0.6±1.3),(0.5±1.6) and (0.9±1.7) mm, respectively. The planning target volume (PTV) margins were calculated respectively as 2.4,2.4 and 3.4 mm according to the formula of M=2.5Σ+0.7δ. The margins of 288 sets of data using the Big Bore CT scanner were calculated as 2.0,2.1 and 1.7 mm, respectively.Conclusions The setup errors using final isocenter marking method are smaller than those using reference point marking method. The result derived from this retrospective study could be used to set the margin between CTV and PTV.
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