| SUN Tao,LI Jian-bin,XU Min,LIU Tong-hai,LIN Xiu-tong,ZHANG Gui-fang.Dosimetric comparison of three-dimensional conformal radiotherapy, intensity-modulated radiotherapy and volumetric modulated arc radiotherapy in partial breast irradiation[J].Chinese Journal of Radiological Medicine and Protection,2012,32(1):74-79 |
| Dosimetric comparison of three-dimensional conformal radiotherapy, intensity-modulated radiotherapy and volumetric modulated arc radiotherapy in partial breast irradiation |
| Received:April 15, 2011 |
| DOI：10.3760/cma.j.issn.0254-5098.2012.01.018 |
| KeyWords:Breast cancer External-beam partial breast irradiation Three-dimensional conformal radiotherapy Intensity-modulated radiotherapy Volumetric modulated arc radiotherapy Dosimetry |
| FundProject:国家自然科学基金(30870742);山东省科技发展计划(2009GG10002019) |
| Author Name | Affiliation | E-mail | | SUN Tao | Department of Radiation Oncology, Shandong Cancer Hospital﹠Institute, Shandong Academy of Medical Sciences, Jinan 250117, China | | | LI Jian-bin | 250117 济南, 山东省放疗三病区 | lijianbin@msn.com | | XU Min | 250117 济南, 山东省放疗三病区 | | | LIU Tong-hai | Department of Radiation Oncology, Shandong Cancer Hospital﹠Institute, Shandong Academy of Medical Sciences, Jinan 250117, China | | | LIN Xiu-tong | Department of Radiation Oncology, Shandong Cancer Hospital﹠Institute, Shandong Academy of Medical Sciences, Jinan 250117, China | | | ZHANG Gui-fang | Department of Radiation Oncology, Shandong Cancer Hospital﹠Institute, Shandong Academy of Medical Sciences, Jinan 250117, China | |
|
| Hits: 3328 |
| Download times: 2187 |
| Abstract:: |
| Objective To compare the dosimetric differences of three-dimensional conformal radiotherapy(3D-CRT), intensity-modulated radiotherapy(IMRT) and volumetric modulated arc radiotherapy(V-MAT) for external beam partial breast irradiation. Methods Twelve patients with breast cancer receiving breast-conserving surgery and external beam partial breast irradiation were enrolled. Three different techniques including 3D-CRT, IMRT and V-MAT were designed for each patient. The dosimetry in the target, the dose to the organs at risk(OAR), the MU and delivery time were compared. Results All three plans met the clinical requirement. 3D-CRT showed the worst conformity in target. V-MAT provided the lowest target coverage and homogeneity in target. 3D-CRT plans showed the lowest values for the V5, V10, mean dose and the highest values for V30 in the ipsilateral lung. No statistically significant differences were observed in V20 of the ipsilateral lung among three plans. V-MAT showed the lowest values in ipsilateral normal breast volume 15, 20 and 25 Gy post-irradiation. For V5, the mean and max dose in heart, the mean dose in contralateral lung and the mean, max dose in thyroid, IMRT and 3D-CRT showed the highest and lowest value respectively(z=-2.94--2.09,P<0.05). The MUs in 3D-CRT, IMRT and V-MAT were 417.6±34.4, 772.8±54.4 and 631.0±109.0, respectively(z=-2.93, -2.76, -2.93,P<0.05). V-MAT significantly reduced the delivery time. Conclusions V-MAT shows significant advantages in reducing the dose in the ipsilateral normal breast and the delivery time compared with 3D-CRT and IMRT. |
| HTML View Full Text View/Add Comment Download reader |
| Close |
|
|
|
